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Mir539 Gene Detail
Summary
  • Symbol
    Mir539
  • Name
    microRNA 539
  • Synonyms
    mir 539, Mirn539, mmu-mir-539
Location &
Maps
more
  • Sequence Map
    Chr12:109694563-109694636 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 60.56 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    80 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3619427
 miRNA gene Chr12:109694563-109694636 (+)
129S1/SvImJ ENSMUSG00200029728
 miRNA gene Chr12:101468330-101468403 (+)
A/J ENSMUSG00195044789
 miRNA gene Chr12:104000240-104000313 (+)
AKR/J ENSMUSG00220039688
 miRNA gene Chr12:101882510-101882583 (+)
BALB/cJ ENSMUSG00180048460
 miRNA gene Chr12:103231487-103231560 (+)
C3H/HeJ ENSMUSG00175049902
 miRNA gene Chr12:105810474-105810547 (+)
C57BL/6NJ ENSMUSG00215047407
 miRNA gene Chr12:102504430-102504503 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007286
 miRNA gene Chr12:104174032-104174105 (+)
CAST/EiJ ENSTCUG00005019589
 miRNA gene Chr12:101982731-101982804 (+)
CBA/J ENSMUSG00210040280
 miRNA gene Chr12:102871931-102872004 (+)
DBA/2J ENSMUSG00185028573
 miRNA gene Chr12:104690479-104690552 (+)
FVB/NJ ENSMUSG00205046601
 miRNA gene Chr12:101916341-101916414 (+)
JF1/MsJ ENSUMUG00000034375
 miRNA gene Chr12:109448590-109448663 (+)
LP/J ENSMUSG00230030511
 miRNA gene Chr12:111733210-111733283 (+)
NOD/ShiLtJ ENSMUSG00190033454
 miRNA gene Chr12:83306755-83306828 (-)
NZO/HlLtJ ENSMUSG00225038109
 miRNA gene Chr12:113492088-113492161 (+)
PWK/PhJ ENSLUMG00010045455
 miRNA gene Chr12:102921098-102921171 (+)
SPRET/EiJ ENSMSPG00010019327
 miRNA gene Chr12:105204138-105204211 (+)
WSB/EiJ ENSIUOG00005008913
 miRNA gene Chr12:101913755-101913828 (+)



Homology
more
  • Human Ortholog
    MIR539, microRNA 539
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR539, microRNA 539
  • Synonyms
    hsa-mir-539, mir-539, MIRN539
  • Links
    NCBI Gene ID: 664612

  • Chr Location
    chr14:101047321-101047398 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    610
  • Tissues
    3
  • Literature Summary
    2
Sequences &
Gene Models
less
  • All Sequences
    24
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 723917 NCBI Gene Model | MGI Sequence Detail 74 C57BL/6J ±  kb
transcript NR_030262 RefSeq | MGI Sequence Detail 74 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 1
    Other 1
Other Database
Links
less
miRBase MI0003520
References
more
  • Summaries
    All 23
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:106122 Sewer A, et al., Identification of clustered microRNAs using an ab initio prediction method. BMC Bioinformatics. 2005;6:267
  • Latest
    J:283772 Liko D, et al., Loss of TSC complex enhances gluconeogenesis via upregulation of Dlk1-Dio3 locus miRNAs. Proc Natl Acad Sci U S A. 2020 Jan 21;117(3):1524-1532
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory