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Mir489 Gene Detail
Summary
  • Symbol
    Mir489
  • Name
    microRNA 489
  • Synonyms
    mir 489, mir-489, Mirn489, mmu-mir-489
Location &
Maps
more
  • Sequence Map
    Chr6:3721897-3722003 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 6, 1.81 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    105 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3619425
miRNA gene Chr6:3721897-3722003 (-)
129S1/SvImJ ENSMUSG00200001840
miRNA gene Chr6:793268-793374 (-)
A/J ENSMUSG00195001981
miRNA gene Chr6:674397-674503 (-)
AKR/J ENSMUSG00220021011
miRNA gene Chr6:586271-586377 (-)
BALB/cJ ENSMUSG00180001525
miRNA gene Chr6:810017-810123 (-)
C3H/HeJ ENSMUSG00175007505
miRNA gene Chr6:638641-638747 (-)
C57BL/6NJ ENSMUSG00215014660
miRNA gene Chr6:762194-762300 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0008004
miRNA gene Chr6:261628-261734 (-)
CAST/EiJ ENSTCUG00005026361
miRNA gene Chr6:688320-688426 (-)
CBA/J ENSMUSG00210021316
miRNA gene Chr6:575723-575829 (-)
DBA/2J ENSMUSG00185025509
miRNA gene Chr6:770288-770394 (-)
FVB/NJ ENSMUSG00205016406
miRNA gene Chr6:777974-778080 (-)
JF1/MsJ ENSUMUG00000012187
miRNA gene Chr6:786918-787024 (-)
LP/J ENSMUSG00230017360
miRNA gene Chr6:1769993-1770099 (-)
NOD/ShiLtJ ENSMUSG00190016936
miRNA gene Chr6:495441-495547 (-)
NZO/HlLtJ ENSMUSG00225019159
miRNA gene Chr6:3588128-3588234 (-)
PWK/PhJ ENSLUMG00010024820
miRNA gene Chr6:581736-581842 (-)
SPRET/EiJ ENSMSPG00010002828
miRNA gene Chr6:427328-427434 (-)
WSB/EiJ ENSIUOG00005004330
miRNA gene Chr6:760183-760289 (-)



Homology
more
  • Human Ortholog
    MIR489, microRNA 489
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR489, microRNA 489
  • Synonyms
    hsa-mir-489, mir-489, MIRN489
  • Links
    NCBI Gene ID: 574442

  • Chr Location
    chr7:93483936-93484019 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Literature Summary
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 723877 NCBI Gene Model | MGI Sequence Detail 107 C57BL/6J ±  kb
transcript NR_030250 RefSeq | MGI Sequence Detail 107 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 1
    Other 1
Other Database
Links
less
miRBase MI0003476
References
more
  • Summaries
    All 20
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:106122 Sewer A, et al., Identification of clustered microRNAs using an ab initio prediction method. BMC Bioinformatics. 2005;6:267
  • Latest
    J:269960 Patel Y, et al., Overexpression of miR-489 derails mammary hierarchy structure and inhibits HER2/neu-induced tumorigenesis. Oncogene. 2018 Aug 13;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory