Mir10a MGI Mouse Gene Detail - MGI:3619064

Symbol

Mir10a
Name

microRNA 10a
Synonyms

MicroRNA-10a, mir 10a, miR-10a, Mirn10a, mmu-mir-10a

Feature Type

miRNA gene
IDs

MGI:3619064
NCBI Gene: 723893
Alliance

gene page

Sequence Map

Chr11:96207991-96208100 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 59.83 cM
Mapping Data

1 experiment

SNPs within 2kb

6 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3619064	miRNA gene	Chr11:96207991-96208100 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0007864	miRNA gene	Chr11:98630326-98630435 (+)
A/J	MGP_AJ_G0007857	miRNA gene	Chr11:94601751-94601860 (+)
AKR/J	MGP_AKRJ_G0007832	miRNA gene	Chr11:97527918-97528027 (+)
BALB/cJ	MGP_BALBcJ_G0007836	miRNA gene	Chr11:95101449-95101558 (+)
C3H/HeJ	MGP_C3HHeJ_G0007782	miRNA gene	Chr11:97659158-97659267 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0008015	miRNA gene	Chr11:101711428-101711537 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0007156	miRNA gene	Chr11:92088338-92088447 (+)
CAST/EiJ	MGP_CASTEiJ_G0007676	miRNA gene	Chr11:98482804-98482913 (+)
CBA/J	MGP_CBAJ_G0007753	miRNA gene	Chr11:105873222-105873331 (+)
DBA/2J	MGP_DBA2J_G0007788	miRNA gene	Chr11:94169190-94169299 (+)
FVB/NJ	MGP_FVBNJ_G0007807	miRNA gene	Chr11:93647930-93648039 (+)
LP/J	MGP_LPJ_G0007866	miRNA gene	Chr11:99166366-99166475 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0007777	miRNA gene	Chr11:105868705-105868814 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0008011	miRNA gene	Chr11:97835382-97835491 (+)
PWK/PhJ	MGP_PWKPhJ_G0007603	miRNA gene	Chr11:95120606-95120715 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0007498	miRNA gene	Chr11:97561914-97562023 (+)
WSB/EiJ	MGP_WSBEiJ_G0007743	miRNA gene	Chr11:97721663-97721772 (+)

Human Ortholog

MIR10A, microRNA 10a

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR10A, microRNA 10a
Synonyms

hsa-mir-10a, mir-10a, MIRN10A, miRNA10A
Links

HGNC:31497

NCBI Gene ID: 406902
Chr Location

chr17:48579838-48579947 (-) GRCh38

MGI Vertebrate Homology

Mir10a stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: MIR10A
Gene Tree

Mir10a

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Phenotype Summary

2 phenotypes from 2 alleles in 2 genetic backgrounds
2 phenotypes from multigenic genotypes
1 images
19 phenotype references

All Mutations and Alleles

8
Targeted

8
Genomic Mutations

4 involving Mir10a
Find Mice (IMSR)

2 strains or lines available

Mice homozygous for a targeted deletion are viable with no observed pathologies. Mice homozygous for a knock-out allele exhibit increased frequency with of high-grade dysplasia and higher incidence of tubule-villous adenomas in Apc^min heterozygotes.

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All GO Annotations

7
GO References

6

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

713
Tissues

5
Literature Summary

9

Images

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

23
RefSeq

1

Ensembl

ENSMUSG00000065519 (Evidence)
NCBI Gene

723893

Representative Sequences				Length	Strain/Species	Flank
	genomic	723893	NCBI Gene Model \| MGI Sequence Detail	110	C57BL/6J	± kb
	transcript	NR_029784	RefSeq \| MGI Sequence Detail	110	C57BL/6

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All nucleic 3

Primer pair 1

Other 2

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miRBase

MI0000685

Summaries

All 45

Developmental Gene Expression 9

Gene Ontology 6

Phenotypes 19
Earliest

J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
Latest

J:329266 Chen CH, et al., Transgenic human HOXB1-9 directs anterior-posterior axial skeleton pattern in Hoxb1-9 deficient mice. Differentiation. 2022 Sep-Oct;127:1-11

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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