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Ccdc185 Gene Detail
Summary
  • Symbol
    Ccdc185
  • Name
    coiled-coil domain containing 185
  • Synonyms
    4922505E12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3618292
    NCBI Gene: 433386
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:182574691-182576745 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 85.92 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    147 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3618292
 protein coding gene Chr1:182574691-182576745 (-)
129S1/SvImJ ENSMUSG00200022135
 protein coding gene Chr1:180342160-180344214 (-)
A/J ENSMUSG00195039082
 protein coding gene Chr1:179928683-179930737 (-)
AKR/J ENSMUSG00220020522
 protein coding gene Chr1:179166309-179168363 (-)
BALB/cJ ENSMUSG00180035129
 protein coding gene Chr1:179993505-179995559 (-)
C3H/HeJ ENSMUSG00175037674
 protein coding gene Chr1:180169182-180171236 (-)
C57BL/6NJ ENSMUSG00215025084
 protein coding gene Chr1:179388499-179390553 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015004
 protein coding gene Chr1:172750215-172752284 (-)
CAST/EiJ ENSTCUG00005040230
 protein coding gene Chr1:177911158-177913215 (-)
CBA/J ENSMUSG00210018996
 protein coding gene Chr1:179812549-179814603 (-)
DBA/2J ENSMUSG00185034326
 protein coding gene Chr1:184431955-184434009 (-)
FVB/NJ ENSMUSG00205024791
 protein coding gene Chr1:178857000-178859054 (-)
JF1/MsJ ENSUMUG00000005109
 protein coding gene Chr1:183447407-183449464 (-)
LP/J ENSMUSG00230021906
 protein coding gene Chr1:184001353-184003407 (-)
NOD/ShiLtJ ENSMUSG00190028654
 protein coding gene Chr1:179845119-179847173 (-)
NZO/HlLtJ ENSMUSG00225010369
 protein coding gene Chr1:187747181-187749235 (-)
PWK/PhJ ENSLUMG00010015760
 protein coding gene Chr1:178680867-178682921 (-)
SPRET/EiJ ENSMSPG00010028433
 protein coding gene Chr1:182168728-182170782 (-)
WSB/EiJ ENSIUOG00005010962
 protein coding gene Chr1:179034900-179036954 (-)



Homology
more
  • Human Ortholog
    CCDC185, coiled-coil domain containing 185
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC185, coiled-coil domain containing 185
  • Synonyms
    C1orf65
  • Links
    NCBI Gene ID: 164127
    UniProt: Q8N715

  • Chr Location
    1q41; chr1:223393415-223395465 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotype references
Male mice homozygous for a knock-out allele are fertile and exhibit normal testis gross appearance, normal testis and epididymis histology and germ cell number, and normal sperm morphology and motility.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 433386 NCBI Gene Model | MGI Sequence Detail 2055 C57BL/6J ±  kb
transcript NM_001033547 RefSeq | MGI Sequence Detail 2055 Not Specified  
polypeptide NP_001028719 RefSeq | MGI Sequence Detail 621 Not Specified  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR029090 Protein of unknown function DUF4659
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 21
    Phenotypes 3
  • Earliest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
  • Latest
    J:385753 Qiu Y, et al., CRISPR/Cas9-mediated Genome-editing Reveals 10 Testis-enriched Genes and One Non-testis-enriched Gene are Dispensable for Male Fecundity in Mice. Andrology. 2025 Nov 10;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory