Sp140l2 Gene Detail

Summary

• Symbol
  Sp140l2
• Name
  Sp140 nuclear body protein like 2
• Synonyms
  4930565N07Rik, C130026I21Rik, OTTMUSG00000029174

• Feature Type
  protein coding gene
• IDs
  MGI:3612702
  NCBI Gene: 620078
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr1:85219007-85260602 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 1, 43.44 cM
• Mapping Data
  3 experiments

Strain
Comparison

• SNPs within 2kb
  291 from dbSNP Build 142
• Strain Annotations
  3

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3612702	protein coding gene	Chr1:84970411-85260602 (-)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	MGP_C57BL6NJ_G0016624	protein coding gene	Chr1:90056263-90061315 (-)
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	MGP_DBA2J_G0016075	protein coding gene	Chr1:82524750-82547889 (-)
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• MGI Vertebrate Homology
  Sp140l2 stringent orthology
  1 mouse;1 rat
  
• Gene Tree
  Sp140l2
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  3
• Chemically induced (other)
  1
• Radiation induced
  1
• Targeted
  1
• Genomic Mutations
  2 involving Sp140l2
• Incidental Mutations
  Mutagenetix
• Find Mice (IMSR)
  27 strains or lines available

Expression

• Assay Results
  706
• cDNA Data
  6

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  69
• RefSeq
  34
• UniProt
  10
• CCDS
  CCDS15109.1, CCDS35636.1

• Ensembl
  ENSMUSG00000052477 (Evidence)
• NCBI Gene
  620078

Representative Sequences			Length	Strain/Species
genomic	620078	NCBI Gene Model | MGI Sequence Detail	41596	C57BL/6J
transcript	NM_175219	RefSeq | MGI Sequence Detail	1971	C57BL/6
polypeptide	NP_780428	RefSeq | MGI Sequence Detail	291	C57BL/6

Protein
Information

• UniProt
  10 Sequences
• InterPro Domains
  IPR004865 HSR domain
  IPR043563 Nuclear body protein Sp110/Sp140/Sp140L-like
  IPR000770 SAND domain
  IPR010919 SAND-like domain superfamily

Molecular
Reagents

• All nucleic 6

  cDNA 6

  
  

  Microarray probesets 2

Other
Accession IDs

MGI:1922557, MGI:3783242, MGI:7467514

References

• Summaries
  All 21

  Phenotypes 5
• Earliest
  J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
• Latest
  J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563