Ly6a2 Gene Detail

Summary

• Symbol
  Ly6a2
• Name
  lymphocyte antigen 6 family member A2
• Synonyms
  I830127L07Rik

• Feature Type
  protein coding gene
  BioType Conflict
  
• IDs
  MGI:3612406
  NCBI Gene: 546643
• Alliance
  genome feature page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr15:75003524-75006673 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 15, 34.29 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  312 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3612406	protein coding gene	Chr15:75003141-75006977 (-)
129S1/SvImJ	ENSMUSG00200053652	pseudogene	Chr15:72111271-72116175 (-)
A/J	ENSMUSG00195051563	pseudogene	Chr15:72082441-72112732 (-)
AKR/J	ENSMUSG00220045781	protein coding gene	Chr15:72101116-72104419 (-)
AKR/J	ENSMUSG00220052964	pseudogene	Chr15:72099724-72104628 (-)
BALB/cJ	ENSMUSG00180054167	pseudogene	Chr15:71941462-71946311 (-)
C3H/HeJ	ENSMUSG00175052983	pseudogene	Chr15:72303361-72308212 (-)
C57BL/6NJ	ENSMUSG00215053138	pseudogene	Chr15:72008797-72013701 (-)
CAROLI/EiJ	no annotation
CAST/EiJ	ENSTCUG00005048260	pseudogene	Chr15:71629895-71634738 (-)
CBA/J	ENSMUSG00210049635	pseudogene	Chr15:72078700-72083547 (-)
DBA/2J	ENSMUSG00185052295	pseudogene	Chr15:72034275-72039181 (-)
FVB/NJ	ENSMUSG00205050826	pseudogene	Chr15:71780169-71785075 (-)
JF1/MsJ	ENSUMUG00000056630	pseudogene	Chr15:71669990-71674912 (-)
LP/J	ENSMUSG00230052882	pseudogene	Chr15:75398338-75403242 (-)
NOD/ShiLtJ	ENSMUSG00190050475	protein coding gene	Chr15:72033850-72037356 (-)
NOD/ShiLtJ	ENSMUSG00190053488	pseudogene	Chr15:72032790-72037637 (-)
NZO/HlLtJ	no annotation
PWK/PhJ	ENSLUMG00010053050	pseudogene	Chr15:71950047-71954929 (-)
SPRET/EiJ	ENSMSPG00010051119	pseudogene	Chr15:73670562-73675550 (-)
WSB/EiJ	ENSIUOG00005050589	pseudogene	Chr15:72083067-72087916 (-)

Homology

• Gene Tree
  Ly6a2
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  24 phenotype references
  

• All Mutations and Alleles
  5
• Chemically induced (other)
  3
• Radiation induced
  2
• Genomic Mutations
  5 involving Ly6a2
• Find Mice (IMSR)
  1 strains or lines available

Expression

• Assay Results
  597
• cDNA Data
  2

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  29
• RefSeq
  4
• UniProt
  1

• Ensembl
  ENSMUSG00000102051 (Evidence)
• NCBI Gene
  546643

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000102051	Ensembl Gene Model | MGI Sequence Detail	3150	C57BL/6J
transcript	ENSMUST00000190944	Ensembl | MGI Sequence Detail	405	Not Applicable
polypeptide	NP_001365169	RefSeq | MGI Sequence Detail	134	C57BL/6

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR018363 CD59 antigen, conserved site
  IPR016054 Ly-6 antigen/uPA receptor-like
  IPR051445 Lymphocyte Antigen 6 Family Modulators
  IPR045860 Snake toxin-like superfamily

Molecular
Reagents

• All nucleic 2

  cDNA 2

Other
Accession IDs

MGI:6278298

References

• Summaries
  All 34

  Diseases 1

  Phenotypes 24
• Earliest
  J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
• Latest
  J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)

TSS for Ly6a2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr134838	Chr15:75006974-75006978 (-)	-303 bp
Tssr134837	Chr15:75006887-75006919 (-)	-230 bp