Spata21 MGI Mouse Gene Detail - MGI:3607787 - spermatogenesis associated 21

Symbol

Spata21
Name

spermatogenesis associated 21

Feature Type

protein coding gene
IDs

MGI:3607787
NCBI Gene: 329972
Alliance

genome feature page
Transcription Start Sites

5 TSS

Sequence Map

Chr4:140815644-140840071 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 4, 73.36 cM
Mapping Data

1 experiment

SNPs within 2kb

809 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3607787	protein coding gene	Chr4:140815631-140840071 (+)
129S1/SvImJ	ENSMUSG00200041850	protein coding gene	Chr4:134233615-134258406 (+)
A/J	ENSMUSG00195032228	protein coding gene	Chr4:135581525-135605961 (+)
AKR/J	ENSMUSG00220044256	protein coding gene	Chr4:134582332-134606775 (+)
BALB/cJ	ENSMUSG00180046230	protein coding gene	Chr4:133222700-133247125 (+)
C3H/HeJ	ENSMUSG00175037515	protein coding gene	Chr4:134249204-134273636 (+)
C57BL/6NJ	ENSMUSG00215049782	protein coding gene	Chr4:135767079-135791510 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0026733	protein coding gene	Chr4:130766467-130792051 (+)
CAST/EiJ	ENSTCUG00005012654	protein coding gene	Chr4:135206152-135230457 (+)
CBA/J	ENSMUSG00210026288	protein coding gene	Chr4:133873172-133897599 (+)
DBA/2J	ENSMUSG00185048613	protein coding gene	Chr4:135385876-135410711 (+)
FVB/NJ	ENSMUSG00205037747	protein coding gene	Chr4:133638676-133661772 (+)
JF1/MsJ	ENSUMUG00000041652	protein coding gene	Chr4:136074942-136099394 (+)
LP/J	ENSMUSG00230034836	protein coding gene	Chr4:139172157-139196951 (+)
NOD/ShiLtJ	ENSMUSG00190021325	protein coding gene	Chr4:133632512-133657339 (+)
NZO/HlLtJ	ENSMUSG00225008530	protein coding gene	Chr4:145124096-145149217 (+)
PWK/PhJ	ENSLUMG00010038389	protein coding gene	Chr4:133071293-133096136 (+)
SPRET/EiJ	ENSMSPG00010029436	protein coding gene	Chr4:135120771-135143641 (+)
WSB/EiJ	ENSIUOG00005039350	protein coding gene	Chr4:133520479-133545197 (+)

Human Ortholog

SPATA21, spermatogenesis associated 21

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SPATA21, spermatogenesis associated 21
Synonyms

spergen-2, spergen2
Links

HGNC:28026

NCBI Gene ID: 374955

UniProt: Q7Z572
Chr Location

1p36.13; chr1:16387117-16437842 (-) GRCh38

MGI Vertebrate Homology

Spata21 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: SPATA21
Gene Tree

Spata21

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
12 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

9
Chemically induced (other)

2
Endonuclease-mediated

5
Gene trapped

1
Targeted

1
Genomic Mutations

3 involving Spata21
Incidental Mutations

APF
Find Mice (IMSR)

25 strains or lines available

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All GO Annotations

1
GO References

1

Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

597
cDNA Data

12

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

35
RefSeq

6
UniProt

1
CCDS

CCDS18863.1

Ensembl

ENSMUSG00000045004 (Evidence)
NCBI Gene

329972

			Length	Strain/Species	Flank
genomic	ENSMUSG00000045004	Ensembl Gene Model \| MGI Sequence Detail	24428	C57BL/6J	± kb
transcript	ENSMUST00000051907	Ensembl \| MGI Sequence Detail	2526	Not Applicable
polypeptide	ENSMUSP00000053080	Ensembl \| MGI Sequence Detail	681	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000015487 spermatogenesis-associated protein 21

(term hierarchy)
InterPro Domains

IPR018247 EF-Hand 1, calcium-binding site

IPR002048 EF-hand domain

IPR011992 EF-hand domain pair

IPR043520 Spermatogenesis-associated protein 21

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All nucleic 13

Genomic 1

cDNA 12

Microarray probesets 2

Summaries

All 29

Gene Ontology 1

Phenotypes 12
Earliest

J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Spata21:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr40025	Chr4:140815649-140815661 (+)	11 bp
Tssr40026	Chr4:140824249-140824261 (+)	8,611 bp
Tssr40027	Chr4:140824392-140824403 (+)	8,754 bp
Tssr40028	Chr4:140827100-140827103 (+)	11,458 bp
Tssr40029	Chr4:140834409-140834418 (+)	18,770 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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