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Mroh8 Gene Detail
Summary
  • Symbol
    Mroh8
  • Name
    maestro heat-like repeat family member 8
  • Synonyms
    4922505G16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3603828
    NCBI Gene: 629499
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:157050470-157121469 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 78.12 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2105 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3603828
 protein coding gene Chr2:157050468-157121612 (-)
129S1/SvImJ ENSMUSG00200015599
 protein coding gene Chr2:153914171-153985416 (-)
A/J ENSMUSG00195019656
 protein coding gene Chr2:154280768-154351851 (-)
AKR/J ENSMUSG00220012892
 protein coding gene Chr2:153588881-153661745 (-)
BALB/cJ ENSMUSG00180048904
 protein coding gene Chr2:153735223-153806238 (-)
C3H/HeJ ENSMUSG00175046702
 protein coding gene Chr2:154485520-154556518 (-)
C57BL/6NJ ENSMUSG00215026421
 protein coding gene Chr2:153899724-153970723 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024572
 protein coding gene Chr2:149168622-149242528 (-)
CAST/EiJ ENSTCUG00005043390
 protein coding gene Chr2:152881421-152954058 (-)
CBA/J ENSMUSG00210016291
 protein coding gene Chr2:154416616-154487618 (-)
DBA/2J ENSMUSG00185048224
 protein coding gene Chr2:154130844-154203699 (-)
FVB/NJ ENSMUSG00205024301
 protein coding gene Chr2:153167605-153238618 (-)
JF1/MsJ ENSUMUG00000021237
 protein coding gene Chr2:153787139-153860008 (-)
LP/J ENSMUSG00230044487
 protein coding gene Chr2:155711866-155783034 (-)
NOD/ShiLtJ ENSMUSG00190034846
 protein coding gene Chr2:153805083-153876086 (-)
NZO/HlLtJ ENSMUSG00225052324
 protein coding gene Chr2:163731957-163802863 (-)
PWK/PhJ ENSLUMG00010044173
 protein coding gene Chr2:153717549-153794901 (-)
SPRET/EiJ ENSMSPG00010028971
 protein coding gene Chr2:156500858-156572199 (-)
WSB/EiJ ENSIUOG00005042404
 protein coding gene Chr2:153495440-153566903 (-)



Homology
more
  • Human Ortholog
    MROH8, maestro heat like repeat family member 8
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MROH8, maestro heat like repeat family member 8
  • Synonyms
    C20orf131, C20orf132
  • Links
    NCBI Gene ID: 140699
    UniProt: Q9H579

  • Chr Location
    20q11.23; chr20:37101167-37179588 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000074627 Ensembl Gene Model | MGI Sequence Detail 71000 C57BL/6J ±  kb
    transcript ENSMUST00000143663 Ensembl | MGI Sequence Detail 3460 Not Applicable  
    polypeptide ENSMUSP00000124362 Ensembl | MGI Sequence Detail 1049 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • InterPro Domains
      IPR011989 Armadillo-like helical
      IPR016024 Armadillo-type fold
      IPR045206 Maestro heat-like repeat-containing protein
      IPR048465 Maestro-like, HEAT-repeats domain
      IPR055406 Maestro/Maestro-like, HEAT-repeats domain
      IPR055408 MROH2B-like, HEAT-repeats domain
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 6

      Microarray probesets 2
    References
    more
    • Summaries
      All 22
      Gene Ontology 2
      Phenotypes 5
    • Earliest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory