About   Help   FAQ
Mindy4 Gene Detail
Summary
  • Symbol
    Mindy4
  • Name
    MINDY lysine 48 deubiquitinase 4
  • Synonyms
    C330043M08Rik, Fam188b, LOC384387
  • Feature Type
    protein coding gene
  • IDs
    MGI:3583959
    NCBI Gene: 330323
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:55180368-55297207 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 27.38 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3168 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3583959
 protein coding gene Chr6:55180337-55297208 (+)
129S1/SvImJ ENSMUSG00200005254
 protein coding gene Chr6:52157345-52272643 (+)
A/J ENSMUSG00195031763
 protein coding gene Chr6:51894521-52009820 (+)
AKR/J ENSMUSG00220005528
 protein coding gene Chr6:51590958-51706253 (+)
BALB/cJ ENSMUSG00180009361
 protein coding gene Chr6:52188429-52303746 (+)
C3H/HeJ ENSMUSG00175034049
 protein coding gene Chr6:51949593-52067983 (+)
C57BL/6NJ ENSMUSG00215014895
 protein coding gene Chr6:52165455-52282309 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028413
 protein coding gene Chr6:49675238-49790577 (+)
CAST/EiJ ENSTCUG00005039043
 protein coding gene Chr6:51425482-51534995 (+)
CBA/J ENSMUSG00210030751
 protein coding gene Chr6:51993957-52109247 (+)
DBA/2J ENSMUSG00185017582
 protein coding gene Chr6:52573509-52688804 (+)
FVB/NJ ENSMUSG00205027440
 protein coding gene Chr6:52223468-52338766 (+)
JF1/MsJ ENSUMUG00000034209
 protein coding gene Chr6:51958705-52067423 (+)
LP/J ENSMUSG00230012523
 protein coding gene Chr6:53654371-53769653 (+)
NOD/ShiLtJ ENSMUSG00190008169
 protein coding gene Chr6:51905077-52020386 (+)
NZO/HlLtJ ENSMUSG00225013040
 protein coding gene Chr6:55645980-55761278 (+)
PWK/PhJ ENSLUMG00010017053
 protein coding gene Chr6:51699511-51808222 (+)
SPRET/EiJ ENSMSPG00010008413
 protein coding gene Chr6:52303431-52412795 (+)
WSB/EiJ ENSIUOG00005019317
 protein coding gene Chr6:52257019-52365822 (+)



Homology
more
  • Human Ortholog
    MINDY4, MINDY lysine 48 deubiquitinase 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MINDY4, MINDY lysine 48 deubiquitinase 4
  • Synonyms
    C7orf67, FAM188B
  • Links
    NCBI Gene ID: 84182
    UniProt: Q4G0A6

  • Chr Location
    7p14.3; chr7:30771417-30892387 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    16
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038022 Ensembl Gene Model | MGI Sequence Detail 116840 C57BL/6J ±  kb
transcript ENSMUST00000053094 Ensembl | MGI Sequence Detail 4270 Not Applicable  
polypeptide ENSMUSP00000061221 Ensembl | MGI Sequence Detail 744 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000030302 probable ubiquitin carboxyl-terminal hydrolase MINDY-4
    (term hierarchy)
  • EC
    3.4.19.12
  • InterPro Domains
    IPR039785 Deubiquitinating enzyme MINDY-3/4
    IPR025257 Deubiquitinating enzyme MINDY-3/4, conserved domain
    IPR059022 MINDY4, N-terminal dimerisation domain
  • GlyGen
    Q3UQI9 2 sites, 1 O-linked glycan (2 sites)
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 2
Other
Accession IDs
less
MGI:2686252, MGI:5897447
References
more
  • Summaries
    All 32
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory