Pigg MGI Mouse Gene Detail - MGI:3576484 - phosphatidylinositol glycan anchor biosynthesis, class G

Symbol

Pigg
Name

phosphatidylinositol glycan anchor biosynthesis, class G
Synonyms

Gpi7

Feature Type

protein coding gene
IDs

MGI:3576484
NCBI Gene: 433931
Alliance

genome feature page
Transcription Start Sites

1 TSS

Sequence Map

Chr5:108460679-108497225 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 5, 52.90 cM
Mapping Data

1 experiment

SNPs within 2kb

877 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3576484	protein coding gene	Chr5:108460475-108497225 (+)
129S1/SvImJ	ENSMUSG00200021167	protein coding gene	Chr5:102210115-102246884 (+)
A/J	ENSMUSG00195034108	protein coding gene	Chr5:101666954-101703688 (+)
AKR/J	ENSMUSG00220043854	protein coding gene	Chr5:101216682-101253421 (+)
BALB/cJ	ENSMUSG00180032363	protein coding gene	Chr5:101819804-101856522 (+)
C3H/HeJ	ENSMUSG00175039678	protein coding gene	Chr5:103861177-103898102 (+)
C57BL/6NJ	ENSMUSG00215016212	protein coding gene	Chr5:101863434-101900175 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0027517	protein coding gene	Chr5:101197088-101231326 (+)
CAST/EiJ	ENSTCUG00005028020	protein coding gene	Chr5:101104172-101141127 (+)
CBA/J	ENSMUSG00210036204	protein coding gene	Chr5:102618748-102655668 (+)
DBA/2J	ENSMUSG00185043919	protein coding gene	Chr5:105523180-105559916 (+)
FVB/NJ	ENSMUSG00205022772	protein coding gene	Chr5:101545367-101582293 (+)
JF1/MsJ	ENSUMUG00000011577	protein coding gene	Chr5:108584637-108621395 (+)
LP/J	ENSMUSG00230031043	protein coding gene	Chr5:109751180-109787943 (+)
NOD/ShiLtJ	ENSMUSG00190041855	protein coding gene	Chr5:101519363-101556093 (+)
NZO/HlLtJ	ENSMUSG00225024891	protein coding gene	Chr5:117373037-117409791 (+)
PWK/PhJ	ENSLUMG00010015286	protein coding gene	Chr5:100570771-100607503 (+)
SPRET/EiJ	ENSMSPG00010039965	protein coding gene	Chr5:103668724-103712104 (+)
WSB/EiJ	ENSIUOG00005035351	protein coding gene	Chr5:104248229-104285146 (+)

Human Ortholog

PIGG, phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group)

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

PIGG, phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group)
Synonyms

EMM, GPI7, LAS21, MRT53, NEDHSCA, PRO4405, RLGS1930
Links

HGNC:25985

NCBI Gene ID: 54872

UniProt: Q5H8A4
Chr Location

4p16.3; chr4:499210-540200 (+) GRCh38

MGI Vertebrate Homology

Pigg stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: PIGG
Gene Tree

Pigg

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
15 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

12
Chemically induced (other)

1
Endonuclease-mediated

3
Gene trapped

3
Radiation induced

1
Targeted

4
Genomic Mutations

2 involving Pigg
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

49 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

12
GO References

6

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

691
Tissues

94
cDNA Data

14
Literature Summary

1

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase pigg

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All Sequences

38
RefSeq

7
UniProt

3
CCDS

CCDS39203.1, CCDS80354.1

Ensembl

ENSMUSG00000029263 (Evidence)
NCBI Gene

433931

			Length	Strain/Species	Flank
genomic	433931	NCBI Gene Model \| MGI Sequence Detail	36547	C57BL/6J	± kb
transcript	NM_001310689	RefSeq \| MGI Sequence Detail	4373	C57BL/6
polypeptide	NP_001297618	RefSeq \| MGI Sequence Detail	983	C57BL/6

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UniProt

3 Sequences
InterPro Domains

IPR017850 Alkaline-phosphatase-like, core domain superfamily

IPR039527 GPI ethanolamine phosphate transferase 2

IPR045687 GPI ethanolamine phosphate transferase 2, C-terminal

IPR037674 GPI ethanolamine phosphate transferase 2, N-terminal

IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase domain
GlyGen

D3Z3Y1 1 site, 1 N-linked glycan (1 site)

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All nucleic 14

cDNA 14

Microarray probesets 1

Summaries

All 35

Developmental Gene Expression 1

Gene Ontology 6

Phenotypes 15
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Pigg:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr47824	Chr5:108460650-108460689 (+)	-9 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/01/2026 MGI 6.24