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Klri1 Gene Detail
Summary
  • Symbol
    Klri1
  • Name
    killer cell lectin-like receptor family I member 1
Location &
Maps
more
  • Sequence Map
    Chr6:129674181-129694095 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 63.44 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    471 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3530275
 protein coding gene Chr6:129673001-129697605 (-)
129S1/SvImJ ENSMUSG00200043254
 protein coding gene Chr6:126771897-126791598 (-)
A/J ENSMUSG00195029636
 protein coding gene Chr6:126181132-126207541 (-)
AKR/J ENSMUSG00220038143
 protein coding gene Chr6:125042702-125069111 (-)
BALB/cJ ENSMUSG00180036444
 protein coding gene Chr6:126518043-126544452 (-)
C3H/HeJ ENSMUSG00175030727
 protein coding gene Chr6:126198235-126224643 (-)
C57BL/6NJ ENSMUSG00215015146
 protein coding gene Chr6:126504455-126524370 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028940
 protein coding gene Chr6:126607019-126623598 (-)
CAST/EiJ ENSTCUG00005037268
 protein coding gene Chr6:126534866-126555848 (-)
CBA/J ENSMUSG00210016418
 protein coding gene Chr6:126218027-126244436 (-)
DBA/2J ENSMUSG00185039250
 protein coding gene Chr6:126916441-126942850 (-)
FVB/NJ ENSMUSG00205025980
 protein coding gene Chr6:125773543-125793442 (-)
JF1/MsJ ENSUMUG00000033837
 protein coding gene Chr6:125535722-125563959 (-)
LP/J ENSMUSG00230039354
 protein coding gene Chr6:128115504-128141822 (-)
NOD/ShiLtJ ENSMUSG00190025652
 protein coding gene Chr6:125928333-125948240 (-)
NZO/HlLtJ ENSMUSG00225014513
 protein coding gene Chr6:130401470-130429886 (-)
PWK/PhJ ENSLUMG00010039815
 protein coding gene Chr6:124726058-124752472 (-)
SPRET/EiJ ENSMSPG00010032858
 protein coding gene Chr6:127468258-127487858 (-)
WSB/EiJ ENSIUOG00005042145
 protein coding gene Chr6:126646818-126666523 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067610 Ensembl Gene Model | MGI Sequence Detail 19915 C57BL/6J ±  kb
transcript ENSMUST00000088046 Ensembl | MGI Sequence Detail 838 Not Applicable  
polypeptide ENSMUSP00000085362 Ensembl | MGI Sequence Detail 248 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR016187 C-type lectin fold
    IPR001304 C-type lectin-like
    IPR016186 C-type lectin-like/link domain superfamily
    IPR033992 Natural killer cell receptor-like, C-type lectin-like domain
    IPR050919 NKG2/CD94 Natural Killer Receptors
  • GlyGen
    B2KG20 3 sites
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1

    Microarray probesets 1
References
more
  • Summaries
    All 19
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:96371 Saether PC, et al., Molecular cloning of KLRI1 and KLRI2, a novel pair of lectin-like natural killer-cell receptors with opposing signalling motifs. Immunogenetics. 2005 Feb;56(11):833-9
  • Latest
    J:189106 Belanger S, et al., Impaired natural killer cell self-education and "missing-self" responses in Ly49-deficient mice. Blood. 2012 Jul 19;120(3):592-602
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory