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Foxr2 Gene Detail
Summary
  • Symbol
    Foxr2
  • Name
    forkhead box R2
  • Synonyms
    EG436240, Foxn6
Location &
Maps
more
  • Sequence Map
    ChrX:151901782-151915857 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 68.46 cM, cytoband F3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    301 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3511682
 protein coding gene ChrX:151897577-151915857 (+)
129S1/SvImJ ENSMUSG00200030824
 protein coding gene ChrX:128690347-128704465 (+)
A/J ENSMUSG00195019793
 protein coding gene ChrX:133695615-133709688 (+)
AKR/J ENSMUSG00220031491
 protein coding gene ChrX:125652149-125666247 (+)
BALB/cJ ENSMUSG00180037140
 protein coding gene ChrX:129071360-129085431 (+)
C3H/HeJ ENSMUSG00175027441
 protein coding gene ChrX:133640452-133654525 (+)
C57BL/6NJ ENSMUSG00215024844
 protein coding gene ChrX:129393532-129407607 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033508
 protein coding gene ChrX:141777559-141794088 (+)
CAST/EiJ ENSTCUG00005032882
 protein coding gene ChrX:131406588-131420682 (+)
CBA/J ENSMUSG00210032976
 protein coding gene ChrX:131094324-131108395 (+)
DBA/2J ENSMUSG00185042007
 protein coding gene ChrX:145915793-145929866 (+)
FVB/NJ ENSMUSG00205021735
 protein coding gene ChrX:129613737-129627812 (+)
JF1/MsJ ENSUMUG00000041539
 protein coding gene ChrX:166087386-166101520 (+)
LP/J ENSMUSG00230011185
 protein coding gene ChrX:152699146-152713260 (+)
NOD/ShiLtJ ENSMUSG00190032600
 protein coding gene ChrX:130132810-130146883 (+)
NZO/HlLtJ ENSMUSG00225041373
 protein coding gene ChrX:156195549-156209599 (+)
PWK/PhJ ENSLUMG00010032976
 protein coding gene ChrX:127611497-127625631 (+)
SPRET/EiJ ENSMSPG00010036895
 protein coding gene ChrX:132482505-132485533 (+)
WSB/EiJ ENSIUOG00005039318
 protein coding gene ChrX:130567190-130581264 (+)



Homology
more
  • Human Ortholog
    FOXR2, forkhead box R2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FOXR2, forkhead box R2
  • Synonyms
    FOXN6
  • Links
    NCBI Gene ID: 139628
    UniProt: Q6PJQ5

  • Chr Location
    Xp11.21; chrX:55623400-55626192 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    10
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    5
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000071665 Ensembl Gene Model | MGI Sequence Detail 14076 C57BL/6J ±  kb
transcript ENSMUST00000096265 Ensembl | MGI Sequence Detail 3210 Not Applicable  
polypeptide ENSMUSP00000093984 Ensembl | MGI Sequence Detail 302 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    Genomic 1
    cDNA 5

    Microarray probesets 1
Other
Accession IDs
less
MGI:3645103
References
more
  • Summaries
    All 33
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:303239 Poh B, et al., Foxr2 promotes formation of CNS-embryonal tumors in a Trp53-deficient background. Neuro Oncol. 2019 Aug 5;21(8):993-1004
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory