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Cpa6 Gene Detail
Summary
  • Symbol
    Cpa6
  • Name
    carboxypeptidase A6
  • Synonyms
    9030616D13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045348
    NCBI Gene: 329093
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:10394945-10790170 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 2.45 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2426 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045348
protein coding gene Chr1:10366016-10790277 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015835
protein coding gene Chr1:7631011-8031522 (-)
A/J MGP_AJ_G0015817
protein coding gene Chr1:7659429-8061113 (-)
AKR/J MGP_AKRJ_G0015776
protein coding gene Chr1:7534989-7946039 (-)
BALB/cJ MGP_BALBcJ_G0015773
protein coding gene Chr1:7388543-7794996 (-)
C3H/HeJ MGP_C3HHeJ_G0015607
protein coding gene Chr1:7487567-7876318 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016227
protein coding gene Chr1:7949133-8375250 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0013948
protein coding gene Chr1:6500287-6864636 (-)
CAST/EiJ MGP_CASTEiJ_G0015187
protein coding gene Chr1:7671732-8079523 (-)
CBA/J MGP_CBAJ_G0015580
protein coding gene Chr1:8158758-8578426 (-)
DBA/2J MGP_DBA2J_G0015679
protein coding gene Chr1:7265293-7669394 (-)
FVB/NJ MGP_FVBNJ_G0015684
protein coding gene Chr1:7183818-7568633 (-)
LP/J MGP_LPJ_G0015751
protein coding gene Chr1:7821181-8233103 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015703
protein coding gene Chr1:8790820-9204427 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016273
protein coding gene Chr1:7464459-7868801 (-)
PWK/PhJ MGP_PWKPhJ_G0014971
protein coding gene Chr1:7140529-7523592 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014751
protein coding gene Chr1:7644516-8037341 (-)
WSB/EiJ MGP_WSBEiJ_G0015251
protein coding gene Chr1:7483135-7869765 (-)



Homology
more
  • Human Ortholog
    CPA6, carboxypeptidase A6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CPA6, carboxypeptidase A6
  • Synonyms
    CPAH, ETL5, FEB11
  • Links
    NCBI Gene ID: 57094
    neXtProt AC: NX_Q8N4T0
    UniProt: Q8N4T0

  • Chr Location
    8q13.2; chr8:67422038-67746378 (-)  GRCh38

Human Diseases
more
  • Diseases
    2 with human CPA6 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042501 Ensembl Gene Model | MGI Sequence Detail 395226 C57BL/6J ±  kb
transcript ENSMUST00000035577 Ensembl | MGI Sequence Detail 1932 Not Applicable  
polypeptide ENSMUSP00000035435 Ensembl | MGI Sequence Detail 438 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 6
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 22
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:99338 Fontenele-Neto JD, et al., Identification and distribution of mouse carboxypeptidase A-6. Brain Res Mol Brain Res. 2005 Jun 13;137(1-2):132-42
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory