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Rtl5 Gene Detail
Summary
  • Symbol
    Rtl5
  • Name
    retrotransposon Gag like 5
  • Synonyms
    6430402L03Rik, Mar5, Mart5, Rgag4
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045324
    NCBI Gene: 331474
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:101110150-101114910 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 45.06 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    139 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045324
 protein coding gene ChrX:101110148-101114942 (-)
129S1/SvImJ ENSMUSG00200038402
 protein coding gene ChrX:82823752-82828512 (-)
A/J ENSMUSG00195037141
 protein coding gene ChrX:86578589-86583349 (-)
AKR/J ENSMUSG00220037125
 protein coding gene ChrX:81269379-81274139 (-)
BALB/cJ ENSMUSG00180039395
 protein coding gene ChrX:83288962-83293722 (-)
C3H/HeJ ENSMUSG00175038544
 protein coding gene ChrX:86949356-86954116 (-)
C57BL/6NJ ENSMUSG00215044852
 protein coding gene ChrX:83479586-83484346 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033295
 protein coding gene ChrX:96313836-96318568 (-)
CAST/EiJ ENSTCUG00005038616
 protein coding gene ChrX:84329745-84334504 (-)
CBA/J ENSMUSG00210038920
 protein coding gene ChrX:83720142-83724902 (-)
DBA/2J ENSMUSG00185040071
 protein coding gene ChrX:96163148-96167908 (-)
FVB/NJ ENSMUSG00205023213
 protein coding gene ChrX:82977879-82982639 (-)
JF1/MsJ ENSUMUG00000019132
 protein coding gene ChrX:116751755-116756516 (-)
LP/J ENSMUSG00230041116
 protein coding gene ChrX:102857249-102862009 (-)
NOD/ShiLtJ ENSMUSG00190027598
 protein coding gene ChrX:82874999-82879759 (-)
NZO/HlLtJ ENSMUSG00225045223
 protein coding gene ChrX:107952528-107957288 (-)
PWK/PhJ ENSLUMG00010033306
 protein coding gene ChrX:82017854-82022596 (-)
SPRET/EiJ ENSMSPG00010038531
 protein coding gene ChrX:86318843-86323601 (-)
WSB/EiJ ENSIUOG00005037975
 protein coding gene ChrX:83401684-83406444 (-)



Homology
more
  • Human Ortholog
    RTL5, retrotransposon Gag like 5
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RTL5, retrotransposon Gag like 5
  • Synonyms
    6430402L03Rik, MAR5, MART5, RGAG4, SIRH8
  • Links
    NCBI Gene ID: 340526
    UniProt: Q5HYW3

  • Chr Location
    Xq13.1; chrX:72127110-72131915 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit impaired dsRNA analog removal.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    652
  • Tissues
    26
  • cDNA Data
    20
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000049191 Ensembl Gene Model | MGI Sequence Detail 4761 C57BL/6J ±  kb
    transcript ENSMUST00000113631 Ensembl | MGI Sequence Detail 4653 Not Applicable  
    polypeptide ENSMUSP00000109261 Ensembl | MGI Sequence Detail 599 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 21
      cDNA 20
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:5906150
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 4
      Phenotypes 7
    • Earliest
      J:96508 Brandt J, et al., Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals. Gene. 2005 Jan 17;345(1):101-11
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    09/08/2026
    MGI 6.24     		The Jackson Laboratory