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Trim52 Gene Detail
Summary
  • Symbol
    Trim52
  • Name
    tripartite motif-containing 52
  • Synonyms
    4921513B05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045276
    NCBI Gene: 212085
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:106343632-106373293 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 56.16 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    762 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045276
 protein coding gene Chr14:106343632-106373296 (+)
129S1/SvImJ ENSMUSG00200018027
 protein coding gene Chr14:94940048-94943122 (+)
A/J ENSMUSG00195004122
 protein coding gene Chr14:95040266-95043340 (+)
AKR/J ENSMUSG00220001104
 protein coding gene Chr14:94467612-94470686 (+)
BALB/cJ ENSMUSG00180010270
 protein coding gene Chr14:94523792-94526866 (+)
C3H/HeJ ENSMUSG00175013758
 protein coding gene Chr14:96415040-96418114 (+)
C57BL/6NJ ENSMUSG00215006302
 protein coding gene Chr14:94597673-94600747 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019584
 protein coding gene Chr14:96029679-96052805 (+)
CAST/EiJ ENSTCUG00005002753
 protein coding gene Chr14:95955163-95958316 (+)
CBA/J ENSMUSG00210013978
 protein coding gene Chr14:95104149-95107223 (+)
DBA/2J ENSMUSG00185010960
 protein coding gene Chr14:100260887-100263955 (+)
FVB/NJ ENSMUSG00205008264
 protein coding gene Chr14:94200447-94203522 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230003190
 protein coding gene Chr14:112127373-112130488 (+)
NOD/ShiLtJ ENSMUSG00190001576
 protein coding gene Chr14:94893048-94896122 (+)
NZO/HlLtJ ENSMUSG00225021282
 protein coding gene Chr14:102530147-102533221 (+)
PWK/PhJ ENSLUMG00010001091
 protein coding gene Chr14:94147125-94150199 (+)
SPRET/EiJ ENSMSPG00010009349
 protein coding gene Chr14:98142428-98145561 (+)
WSB/EiJ ENSIUOG00005006270
 protein coding gene Chr14:94081557-94084625 (+)



Homology
more
  • Human Ortholog
    TRIM52, tripartite motif containing 52
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRIM52, tripartite motif containing 52
  • Synonyms
    RNF102
  • Links
    NCBI Gene ID: 84851
    UniProt: Q96A61

  • Chr Location
    5q35.3; chr5:181249062-181262068 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022113 Ensembl Gene Model | MGI Sequence Detail 29662 C57BL/6J ±  kb
transcript ENSMUST00000022708 Ensembl | MGI Sequence Detail 3075 Not Applicable  
polypeptide ENSMUSP00000022708 Ensembl | MGI Sequence Detail 233 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR050143 Tripartite motif-containing
    IPR013083 Zinc finger, RING/FYVE/PHD-type
    IPR001841 Zinc finger, RING-type
    IPR017907 Zinc finger, RING-type, conserved site
  • GlyGen
    Q8CDV4 1 site
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 23
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:67314 Roix J, et al., Molecular and functional mapping of the piebald deletion complex on mouse chromosome 14. Genetics. 2001 Feb;157(2):803-15
  • Latest
    J:382249 Ma JP, et al., TRIM52 aggravated inflammation and pyroptosis in dextran sulfate sodium-induced inflammatory bowel disease through activation of the TLR4/NF-kappaBs pathway. Allergol Immunopathol (Madr). 2023;51(1):159-167
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory