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Mettl25 Gene Detail
Summary
  • Symbol
    Mettl25
  • Name
    methyltransferase like 25
  • Synonyms
    BC067068
  • Feature Type
    protein coding gene
  • IDs
    MGI:3041259
    NCBI Gene: 216292
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:105599050-105677241 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 55.12 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2579 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3041259
 protein coding gene Chr10:105599050-105677246 (-)
129S1/SvImJ ENSMUSG00200010602
 protein coding gene Chr10:101977504-102055696 (-)
A/J ENSMUSG00195007861
 protein coding gene Chr10:102432217-102510433 (-)
AKR/J ENSMUSG00220024144
 protein coding gene Chr10:101993544-102071700 (-)
BALB/cJ ENSMUSG00180021900
 protein coding gene Chr10:102438992-102517202 (-)
C3H/HeJ ENSMUSG00175015135
 protein coding gene Chr10:102363222-102441421 (-)
C57BL/6NJ ENSMUSG00215008968
 protein coding gene Chr10:102068884-102147087 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015780
 protein coding gene Chr10:98912808-98987194 (-)
CAST/EiJ ENSTCUG00005005420
 protein coding gene Chr10:101565719-101636053 (-)
CBA/J ENSMUSG00210011411
 protein coding gene Chr10:102254083-102332277 (-)
DBA/2J ENSMUSG00185018125
 protein coding gene Chr10:102381293-102459494 (-)
FVB/NJ ENSMUSG00205003237
 protein coding gene Chr10:101870664-101948907 (-)
JF1/MsJ ENSUMUG00000007051
 protein coding gene Chr10:103806144-103882596 (-)
LP/J ENSMUSG00230012043
 protein coding gene Chr10:104342709-104420902 (-)
NOD/ShiLtJ ENSMUSG00190024766
 protein coding gene Chr10:102472800-102550942 (-)
NZO/HlLtJ ENSMUSG00225040407
 protein coding gene Chr10:108598199-108676399 (-)
PWK/PhJ ENSLUMG00010013645
 protein coding gene Chr10:102058837-102138265 (-)
SPRET/EiJ ENSMSPG00010005307
 protein coding gene Chr10:103929902-104002557 (-)
WSB/EiJ ENSIUOG00005010162
 protein coding gene Chr10:102149804-102241908 (-)



Homology
more
  • Human Ortholog
    METTL25, methyltransferase like 25
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    METTL25, methyltransferase like 25
  • Synonyms
    C12orf26
  • Links
    NCBI Gene ID: 84190
    UniProt: Q8N6Q8

  • Chr Location
    12q21.31; chr12:82358500-82479239 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    693
  • Tissues
    12
  • cDNA Data
    9
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000036009 Ensembl Gene Model | MGI Sequence Detail 78192 C57BL/6J ±  kb
    transcript ENSMUST00000046638 Ensembl | MGI Sequence Detail 2033 Not Applicable  
    polypeptide ENSMUSP00000038665 Ensembl | MGI Sequence Detail 597 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 2
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 1
      Phenotypes 17
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory