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Mrgpra1 Gene Detail
Summary
  • Symbol
    Mrgpra1
  • Name
    MAS-related GPR, member A1
  • Synonyms
    MrgA1
Location &
Maps
more
  • Sequence Map
    Chr7:46984623-47003988 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 30.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1176 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3033095
 protein coding gene Chr7:46984623-47003988 (-)
129S1/SvImJ ENSMUSG00200031083
 protein coding gene Chr7:34602785-34622172 (-)
A/J ENSMUSG00195044308
 protein coding gene Chr7:38619160-38638544 (-)
AKR/J ENSMUSG00220007717
 protein coding gene Chr7:32930386-32949771 (-)
BALB/cJ ENSMUSG00180041837
 protein coding gene Chr7:35494627-35514008 (-)
C3H/HeJ ENSMUSG00175027815
 protein coding gene Chr7:36038688-36058071 (-)
C57BL/6NJ ENSMUSG00215042447
 protein coding gene Chr7:35278183-35297564 (-)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005045389
 protein coding gene Chr7:39040415-39059601 (-)
CBA/J ENSMUSG00210036324
 protein coding gene Chr7:36388997-36408382 (-)
DBA/2J ENSMUSG00185028175
 protein coding gene Chr7:40285536-40304921 (-)
FVB/NJ ENSMUSG00205031337
 protein coding gene Chr7:35917816-35937184 (-)
JF1/MsJ ENSUMUG00000020307
 protein coding gene Chr7:44776390-44795429 (-)
LP/J no annotation
NOD/ShiLtJ ENSMUSG00190043201
 protein coding gene Chr7:36261284-36280652 (-)
NZO/HlLtJ ENSMUSG00225013308
 protein coding gene Chr7:43913019-43932404 (-)
PWK/PhJ ENSLUMG00010043110
 protein coding gene Chr7:35234675-35270092 (-)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005029294
 protein coding gene Chr7:36784106-36803278 (-)



Homology
more
  • Human Ortholog
    MRGPRX3, MAS related GPR family member X3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRGPRX3, MAS related GPR family member X3
  • Synonyms
    GPCR, MRGX3, SNSR1, SNSR2
  • Links
    NCBI Gene ID: 117195
    UniProt: Q96LB0

  • Chr Location
    11p15.1; chr11:18120955-18138488 (+)  GRCh38
  • Human Ortholog
    MRGPRX4, MAS related GPR family member X4
  • Synonyms
    GPCR, MRGX4, SNSR6
  • Links
    NCBI Gene ID: 117196
    UniProt: Q96LA9

  • Chr Location
    11p15.1; chr11:18172837-18174280 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    22 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    603
  • Tissues
    3
  • cDNA Data
    2
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 233221 NCBI Gene Model | MGI Sequence Detail 19366 C57BL/6J ±  kb
transcript NM_153095 RefSeq | MGI Sequence Detail 1088 C57BL/6  
polypeptide Q91WW5 UniProt | EBI | MGI Sequence Detail 304 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 2
    Other 2

    Microarray probesets 2
References
more
  • Summaries
    All 50
    Developmental Gene Expression 3
    Gene Ontology 9
    Phenotypes 22
  • Earliest
    J:71586 Dong X, et al., A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Cell. 2001 Sep 7;106(5):619-32
  • Latest
    J:391224 Roger A, et al., Sensory neuron production of substance P and TAFA4 promotes disease tolerance during viral infection. Immunity. 2026 Mar 10;59(3):682-699.e8
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory