Ugt1a7c MGI Mouse Gene Detail - MGI:3032636 - UDP glucuronosyltransferase 1 family, polypeptide A7C

Symbol

Ugt1a7c
Name

UDP glucuronosyltransferase 1 family, polypeptide A7C
Synonyms

A10'

Feature Type

protein coding gene
IDs

MGI:3032636
NCBI Gene: 394432
Member of

Ugt1 cluster
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

Chr1:88022784-88147724 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 44.50 cM
Mapping Data

1 experiment

SNPs within 2kb

1213 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3032636	protein coding gene	Chr1:88022723-88147724 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0016277	protein coding gene	Chr1:89548669-89629383 (+)
A/J	MGP_AJ_G0016257	protein coding gene	Chr1:86151556-86336423 (+)
AKR/J	MGP_AKRJ_G0016218	protein coding gene	Chr1:88709497-88912949 (+)
BALB/cJ	MGP_BALBcJ_G0016214	protein coding gene	Chr1:86315354-86473447 (+)
C3H/HeJ	MGP_C3HHeJ_G0016042	protein coding gene	Chr1:88975081-89123352 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0016672	protein coding gene	Chr1:92825457-92997357 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0014390	protein coding gene	Chr1:80583529-80708870 (+)
CAST/EiJ	MGP_CASTEiJ_G0015628	protein coding gene	Chr1:88190952-88341680 (+)
CBA/J	MGP_CBAJ_G0016018	protein coding gene	Chr1:95808826-95996187 (+)
DBA/2J	MGP_DBA2J_G0016121	protein coding gene	Chr1:85437991-85578045 (+)
FVB/NJ	MGP_FVBNJ_G0016120	protein coding gene	Chr1:84516638-84659651 (+)
LP/J	MGP_LPJ_G0016192	protein coding gene	Chr1:90538875-90704614 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0016146	protein coding gene	Chr1:99051160-99345401 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0016714	protein coding gene	Chr1:88797356-88954939 (+)
PWK/PhJ	MGP_PWKPhJ_G0015414	protein coding gene	Chr1:84845768-84941799 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0015195	protein coding gene	Chr1:87776597-87877022 (+)
WSB/EiJ	MGP_WSBEiJ_G0015690	protein coding gene	Chr1:88531228-88630309 (+)

Human Ortholog

UGT1A10, UDP glucuronosyltransferase family 1 member A10

Vertebrate Orthologs

7

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

UGT1A10, UDP glucuronosyltransferase family 1 member A10
Synonyms

GNT1, hUG-BR1, UDPGT, UGT1, UGT1-01, UGT1.1, UGT1-10, UGT1.10, UGT1A, UGT-1A, UGT1A1, UGT1J, UGT-1J
Links

HGNC:12531

NCBI Gene ID: 54575

neXtProt AC: NX_Q9HAW8

UniProt: Q9HAW8
Chr Location

2q37.1; chr2:233636448-233773300 (+) GRCh38

Human Ortholog

UGT1A7, UDP glucuronosyltransferase family 1 member A7
Synonyms

GNT1, hUG-BR1, UDPGT, UDPGT 1-7, UGT1, UGT1-01, UGT1-07, UGT1.1, UGT1.7, UGT1A, UGT-1A, UGT1A1, UGT1G, UGT-1G
Links

HGNC:12539

NCBI Gene ID: 54577

neXtProt AC: NX_Q9HAW7

UniProt: Q9HAW7
Chr Location

2q37.1; chr2:233681901-233773300 (+) GRCh38

Human Ortholog

UGT1A8, UDP glucuronosyltransferase family 1 member A8
Synonyms

GNT1, hUG-BR1, UDPGT, UDPGT 1-1, UDPGT 1-8, UGT1, UGT1-01, UGT1-08, UGT1.1, UGT1.8, UGT1A, UGT-1A, UGT1A1, UGT1A8S, UGT1H, UGT-1H
Links

HGNC:12540

NCBI Gene ID: 54576

neXtProt AC: NX_Q9HAW9

UniProt: Q9HAW9
Chr Location

2q37.1; chr2:233617633-233773300 (+) GRCh38

Human Ortholog

UGT1A9, UDP glucuronosyltransferase family 1 member A9
Synonyms

HLUGP4, LUGP4, UDPGT, UDPGT 1-9, UGT1-09, UGT1-9, UGT1.9, UGT1A9S, UGT1AI, UGT1I, UGT-1I
Links

HGNC:12541

NCBI Gene ID: 54600

neXtProt AC: NX_O60656

UniProt: O60656
Chr Location

2q37.1; chr2:233671898-233773300 (+) GRCh38

MGI Vertebrate Homology

Ugt1a7c stringent orthology
4 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: UGT1A10, UGT1A7, UGT1A8, UGT1A9
Gene Tree

Ugt1a7c

Diseases

2 with human UGT1A7 associations

				Human Disease	Mouse Models
				alcoholic pancreatitis IDs alcoholic pancreatitis DOID:4988 MESH:D019512 UMLS_CUI:C0376670
				pancreatic cancer IDs pancreatic cancer DOID:1793 DOID:14356 DOID:1797 DOID:3588 DOID:9859 ICD10CM:C25.0 ICD10CM:C25.1 ICD10CM:C25.2 ICD9CM:157.0 ICD9CM:157.1 ICD9CM:157.2 ICD9CM:157.8 KEGG:05212 MESH:D010190 NCI:C3305 ORDO:1333 ORDO:217074 UMLS_CUI:C0030297 UMLS_CUI:C0153458 UMLS_CUI:C0153459 UMLS_CUI:C0153460 UMLS_CUI:C0153463

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

4 phenotype references

All Mutations and Alleles

2
Chemically induced (other)

1
Radiation induced

1
Genomic Mutations

2 involving Ugt1a7c
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

22 strains or lines available

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All GO Annotations

41
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

859
Tissues

99
cDNA Data

11
Literature Summary

2

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

41
RefSeq

2
UniProt

1
CCDS

CCDS15139.1

Ensembl

ENSMUSG00000090124 (Evidence)
NCBI Gene

394432

			Length	Strain/Species	Flank
genomic	ENSMUSG00000090124	Ensembl Gene Model \| MGI Sequence Detail	124941	C57BL/6J	± kb
transcript	ENSMUST00000058237	Ensembl \| MGI Sequence Detail	3231	Not Applicable
polypeptide	ENSMUSP00000058683	Ensembl \| MGI Sequence Detail	531	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000017223 UDP-glucuronosyltransferase 1A7

(term hierarchy)

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All nucleic 11

cDNA 11

Summaries

All 23

Developmental Gene Expression 2

Gene Ontology 5

Phenotypes 4
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Ugt1a7c:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr7935	Chr1:88022725-88022732 (+)	-55 bp
Tssr7936	Chr1:88022776-88022810 (+)	9 bp
Tssr7937	Chr1:88022817-88022843 (+)	46 bp
Tssr7938	Chr1:88022851-88022856 (+)	70 bp
Tssr7939	Chr1:88023300-88023314 (+)	523 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23