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Arl5c Gene Detail
Summary
  • Symbol
    Arl5c
  • Name
    ADP-ribosylation factor-like 5C
  • Synonyms
    Arl12
  • Feature Type
    protein coding gene
  • IDs
    MGI:3028577
    NCBI Gene: 217151
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:97880404-97887007 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 61.47 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    297 from dbSNP Build 142
  • Strain Annotations
    25
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3028577
 protein coding gene Chr11:97880404-97887109 (-)
129S1/SvImJ ENSMUSG00200051748
 protein coding gene Chr11:95127546-95134141 (-)
A/J ENSMUSG00195047226
 protein coding gene Chr11:94850413-94857015 (-)
AKR/J ENSMUSG00220048931
 protein coding gene Chr11:95109523-95110235 (-)
AKR/J ENSMUSG00220048923
 protein coding gene Chr11:95109809-95116131 (-)
BALB/cJ ENSMUSG00180051041
 protein coding gene Chr11:95122179-95122891 (-)
BALB/cJ ENSMUSG00180051053
 protein coding gene Chr11:95122465-95128793 (-)
C3H/HeJ ENSMUSG00175044798
 protein coding gene Chr11:95107594-95114208 (-)
C57BL/6NJ ENSMUSG00215051881
 protein coding gene Chr11:94698780-94705100 (-)
C57BL/6NJ ENSMUSG00215051875
 protein coding gene Chr11:94698494-94699206 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017071
 protein coding gene Chr11:93774867-93781010 (-)
CAST/EiJ ENSTCUG00005050327
 protein coding gene Chr11:94561086-94567741 (-)
CBA/J ENSMUSG00210052587
 protein coding gene Chr11:94812481-94813193 (-)
CBA/J ENSMUSG00210052577
 protein coding gene Chr11:94812767-94819081 (-)
DBA/2J ENSMUSG00185043604
 protein coding gene Chr11:95157488-95164094 (-)
FVB/NJ ENSMUSG00205029726
 protein coding gene Chr11:95024394-95030996 (-)
JF1/MsJ ENSUMUG00000031090
 protein coding gene Chr11:95460142-95466749 (-)
LP/J ENSMUSG00230050161
 protein coding gene Chr11:96210415-96217009 (-)
NOD/ShiLtJ ENSMUSG00190051188
 protein coding gene Chr11:95199949-95206265 (-)
NOD/ShiLtJ ENSMUSG00190051169
 protein coding gene Chr11:95199663-95200375 (-)
NZO/HlLtJ ENSMUSG00225049769
 protein coding gene Chr11:98263973-98270295 (-)
NZO/HlLtJ ENSMUSG00225049749
 protein coding gene Chr11:98263687-98264399 (-)
PWK/PhJ ENSLUMG00010048531
 protein coding gene Chr11:95012388-95019065 (-)
SPRET/EiJ ENSMSPG00010049130
 protein coding gene Chr11:95511458-95517641 (-)
WSB/EiJ ENSIUOG00005044132
 protein coding gene Chr11:94963488-94970078 (-)



Homology
more
  • Human Ortholog
    ARL5C, ARF like GTPase 5C
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARL5C, ARF like GTPase 5C
  • Synonyms
    ARL12
  • Links
    NCBI Gene ID: 390790
    UniProt: A6NH57

  • Chr Location
    17q12; chr17:39156732-39167484 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    611
  • Tissues
    8
  • cDNA Data
    18
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000038352 Ensembl Gene Model | MGI Sequence Detail 6604 C57BL/6J ±  kb
    transcript ENSMUST00000042971 Ensembl | MGI Sequence Detail 1571 Not Applicable  
    polypeptide ENSMUSP00000037214 Ensembl | MGI Sequence Detail 179 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000031015 putative ADP-ribosylation factor-like protein 5C
      (term hierarchy)
    • InterPro Domains
      IPR027417 P-loop containing nucleoside triphosphate hydrolase
      IPR006689 Small GTPase superfamily, ARF/SAR type
      IPR024156 Small GTPase superfamily, ARF type
      IPR005225 Small GTP-binding domain
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 18

      Microarray probesets 2
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 11
    • Earliest
      J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory