Pax6os1 Gene Detail

Summary

• Symbol
  Pax6os1
• Name
  paired box 6 opposite strand 1
• Synonyms
  4831410G09Rik

• Feature Type
  antisense lncRNA gene
  BioType Conflict
  
• IDs
  MGI:3028033
  NCBI Gene: 402728
• Alliance
  genome feature page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr2:105366425-105500675 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 2, 55.25 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  3184 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3028033	antisense lncRNA gene	Chr2:105366414-105500863 (-)
129S1/SvImJ	ENSMUSG00200008104	lncRNA gene	Chr2:102195474-102324631 (-)
A/J	ENSMUSG00195032100	lncRNA gene	Chr2:102356786-102485929 (-)
AKR/J	ENSMUSG00220005065	lncRNA gene	Chr2:102102225-102231356 (-)
BALB/cJ	ENSMUSG00180033645	lncRNA gene	Chr2:102152215-102281360 (-)
C3H/HeJ	ENSMUSG00175033355	lncRNA gene	Chr2:102448255-102580476 (-)
C57BL/6NJ	ENSMUSG00215025928	lncRNA gene	Chr2:102253520-102387722 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0003228	antisense lncRNA gene	Chr2:99016778-99137314 (-)
CAST/EiJ	ENSTCUG00005005960	lncRNA gene	Chr2:101519885-101641593 (-)
CBA/J	ENSMUSG00210040094	lncRNA gene	Chr2:102429885-102559027 (-)
DBA/2J	ENSMUSG00185040260	lncRNA gene	Chr2:102148843-102277951 (-)
FVB/NJ	ENSMUSG00205018837	lncRNA gene	Chr2:101488297-101617335 (-)
JF1/MsJ	ENSUMUG00000004000	lncRNA gene	Chr2:101857795-101990103 (-)
LP/J	ENSMUSG00230006561	lncRNA gene	Chr2:103898125-104027251 (-)
NOD/ShiLtJ	ENSMUSG00190016443	lncRNA gene	Chr2:102276752-102405905 (-)
NZO/HlLtJ	ENSMUSG00225008799	lncRNA gene	Chr2:111801954-111936111 (-)
PWK/PhJ	ENSLUMG00010024690	lncRNA gene	Chr2:101866854-101992982 (-)
SPRET/EiJ	ENSMSPG00010039066	lncRNA gene	Chr2:103902248-104035944 (-)
WSB/EiJ	ENSIUOG00005032216	lncRNA gene	Chr2:101951528-102080612 (-)

Homology

• Gene Tree
  Pax6os1
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  6 phenotype references
  

• All Mutations and Alleles
  5
• Chemically induced (other)
  1
• Endonuclease-mediated
  1
• Radiation induced
  1
• Spontaneous
  2
• Genomic Mutations
  4 involving Pax6os1
• Find Mice (IMSR)
  0 strains or lines available

Mice homozygous for a null allele exhibit normal weight gain, glucose tolerance, and insulin secretion whether fed standard chow or a high-fat diet.

Expression

• Assay Results
  605
• Tissues
  8
• cDNA Data
  1
• Literature Summary
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  36
• RefSeq
  1

• Ensembl
  ENSMUSG00000086029 (Evidence)
• NCBI Gene
  402728

Representative Sequences			Length	Strain/Species
genomic	402728	NCBI Gene Model | MGI Sequence Detail	134251	C57BL/6J
transcript	NR_002867	RefSeq | MGI Sequence Detail	1464	C57BL/6

Molecular
Reagents

• All nucleic 2

  cDNA 1

  Primer pair 1

  
  

  Microarray probesets 1

References

• Summaries
  All 17

  Developmental Gene Expression 1

  Phenotypes 6
• Earliest
  J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
• Latest
  J:375987 Lopez-Noriega L, et al., Roles for the long non-coding RNA Pax6os1/PAX6-AS1 in pancreatic beta cell function. iScience. 2025 Jan 17;28(1):111518

TSS for Pax6os1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr25563	Chr2:105500646-105500667 (-)	18 bp
Tssr25562	Chr2:105500636-105500643 (-)	35 bp