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Ifitm6 Gene Detail
Summary
  • Symbol
    Ifitm6
  • Name
    interferon induced transmembrane protein 6
  • Synonyms
    fragilis5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2686976
    NCBI Gene: 213002
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:140595725-140596805 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 86.26 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2686976
 protein coding gene Chr7:140595612-140597837 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033206
 protein coding gene Chr7:146165980-146167060 (-)
A/J MGP_AJ_G0033188
 protein coding gene Chr7:142003613-142004693 (-)
AKR/J MGP_AKRJ_G0033120
 protein coding gene Chr7:145905266-145906347 (-)
BALB/cJ MGP_BALBcJ_G0033189
 protein coding gene Chr7:141740773-141741853 (-)
C3H/HeJ MGP_C3HHeJ_G0032903
 protein coding gene Chr7:145654829-145655909 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033700
 protein coding gene Chr7:151513743-151514823 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030673
 protein coding gene Chr7:143212927-143214010 (-)
CAST/EiJ MGP_CASTEiJ_G0032233
 protein coding gene Chr7:137962533-137963613 (-)
CBA/J MGP_CBAJ_G0032875
 protein coding gene Chr7:156627114-156628194 (-)
DBA/2J MGP_DBA2J_G0033028
 protein coding gene Chr7:139952143-139953223 (-)
FVB/NJ MGP_FVBNJ_G0032980
 protein coding gene Chr7:139853750-139854830 (-)
LP/J MGP_LPJ_G0033122
 protein coding gene Chr7:147666208-147667288 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033013
 protein coding gene Chr7:157307361-157308441 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033720
 protein coding gene Chr7:144883840-144884920 (-)
PWK/PhJ MGP_PWKPhJ_G0031937
 protein coding gene Chr7:133216151-133217231 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031784
 protein coding gene Chr7:131705177-131706258 (-)
WSB/EiJ MGP_WSBEiJ_G0032344
 protein coding gene Chr7:145827485-145828565 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    719
  • Tissues
    10
  • cDNA Data
    10
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 213002 NCBI Gene Model | MGI Sequence Detail 1081 C57BL/6J ±  kb
transcript NM_001033632 RefSeq | MGI Sequence Detail 541 Not Specified  
polypeptide NP_001028804 RefSeq | MGI Sequence Detail 104 Not Specified  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR007593 CD225/Dispanin family
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 18
  • Earliest
    J:65007 Cattanach BM, et al., Two imprinted gene mutations: three phenotypes. Hum Mol Genet. 2000 Sep 22;9(15):2263-73
  • Latest
    J:332021 Campbell RA, et al., IFITM3 regulates fibrinogen endocytosis and platelet reactivity in nonviral sepsis. J Clin Invest. 2022 Dec 1;132(23)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
01/17/2023
MGI 6.22 		The Jackson Laboratory