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Nxpe3 Gene Detail
Summary
  • Symbol
    Nxpe3
  • Name
    neurexophilin and PC-esterase domain family, member 3
  • Synonyms
    Fam55c, LOC208684, LOC385658
  • Feature Type
    protein coding gene
  • IDs
    MGI:2686598
    NCBI Gene: 385658
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:55660316-55715648 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 33.65 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2070 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2686598
 protein coding gene Chr16:55660316-55717467 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022881
 protein coding gene Chr16:54925880-54985180 (-)
A/J MGP_AJ_G0022848
 protein coding gene Chr16:52575190-52627995 (-)
AKR/J MGP_AKRJ_G0022820
 protein coding gene Chr16:54225436-54284433 (-)
BALB/cJ MGP_BALBcJ_G0022848
 protein coding gene Chr16:52675303-52726864 (-)
C3H/HeJ MGP_C3HHeJ_G0022611
 protein coding gene Chr16:54423771-54482271 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023296
 protein coding gene Chr16:56466286-56526652 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0022138
 protein coding gene Chr16:54827939-54886669 (-)
CBA/J MGP_CBAJ_G0022584
 protein coding gene Chr16:58731771-58799610 (-)
DBA/2J MGP_DBA2J_G0022716
 protein coding gene Chr16:52319849-52371680 (-)
FVB/NJ MGP_FVBNJ_G0022691
 protein coding gene Chr16:52091649-52146549 (-)
LP/J MGP_LPJ_G0022783
 protein coding gene Chr16:54743008-54798561 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022709
 protein coding gene Chr16:59049447-59105473 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023311
 protein coding gene Chr16:54387977-54438603 (-)
PWK/PhJ MGP_PWKPhJ_G0021877
 protein coding gene Chr16:52664670-52724308 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021707
 protein coding gene Chr16:54194425-54248456 (-)
WSB/EiJ MGP_WSBEiJ_G0022182
 protein coding gene Chr16:54404420-54470401 (-)



Homology
more
  • Human Ortholog
    NXPE3, neurexophilin and PC-esterase domain family member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NXPE3, neurexophilin and PC-esterase domain family member 3
  • Synonyms
    FAM55C, MST115, MSTP115
  • Links
    NCBI Gene ID: 91775
    UniProt: Q969Y0

  • Chr Location
    3q12.3; chr3:101779177-101843743 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000075033 Ensembl Gene Model | MGI Sequence Detail 55333 C57BL/6J ±  kb
transcript ENSMUST00000099705 Ensembl | MGI Sequence Detail 6436 Not Applicable  
polypeptide ENSMUSP00000097296 Ensembl | MGI Sequence Detail 559 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR014756 Immunoglobulin E-set
    IPR013783 Immunoglobulin-like fold
    IPR026845 Neurexophilin/NXPE
  • GlyGen
    B9EKK6 2 sites, 1 N-linked glycan (2 sites)
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 3
Other
Accession IDs
less
MGI:2685457
References
more
  • Summaries
    All 20
    Phenotypes 2
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory