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Nckap5 Gene Detail
Summary
  • Symbol
    Nckap5
  • Name
    NCK-associated protein 5
  • Synonyms
    D130011D22Rik, E030049G20Rik, LOC380609
  • Feature Type
    protein coding gene
  • IDs
    MGI:2686394
    NCBI Gene: 210356
  • Alliance
    gene page
  • Transcription Start Sites
    22 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:125841373-126758529 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 54.70 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    7580 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2686394
 protein coding gene Chr1:125841357-126758536 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016418
 protein coding gene Chr1:129027862-129990893 (-)
A/J MGP_AJ_G0016401
 protein coding gene Chr1:124279847-125169575 (-)
AKR/J MGP_AKRJ_G0016366
 protein coding gene Chr1:127911741-128847261 (-)
BALB/cJ MGP_BALBcJ_G0016361
 protein coding gene Chr1:124636424-125543457 (-)
C3H/HeJ MGP_C3HHeJ_G0016187
 protein coding gene Chr1:128113283-129044027 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016822
 protein coding gene Chr1:133898104-134893293 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014535
 protein coding gene Chr1:117681370-118565720 (-)
CAST/EiJ MGP_CASTEiJ_G0015768
 protein coding gene Chr1:127036679-127990999 (-)
CBA/J MGP_CBAJ_G0016160
 protein coding gene Chr1:138391255-139419984 (-)
DBA/2J MGP_DBA2J_G0016266
 protein coding gene Chr1:123283752-124201668 (-)
FVB/NJ MGP_FVBNJ_G0016265
 protein coding gene Chr1:122024984-122943270 (-)
LP/J MGP_LPJ_G0016337
 protein coding gene Chr1:130375815-131337762 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016290
 protein coding gene Chr1:144354345-145353076 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016858
 protein coding gene Chr1:127684765-128631796 (-)
PWK/PhJ MGP_PWKPhJ_G0015554
 protein coding gene Chr1:122261669-123171792 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015342
 protein coding gene Chr1:126630856-127580484 (-)
WSB/EiJ MGP_WSBEiJ_G0015830
 protein coding gene Chr1:127636867-128590545 (-)



Homology
more
  • Human Ortholog
    NCKAP5, NCK associated protein 5
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NCKAP5, NCK associated protein 5
  • Synonyms
    ERIH1, ERIH2, NAP5
  • Links
    NCBI Gene ID: 344148
    neXtProt AC: NX_O14513
    UniProt: O14513

  • Chr Location
    2q21.2; chr2:132671788-133674836 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
DNA-templated transcription
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    877
  • Tissues
    19
  • cDNA Data
    30
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 210356 NCBI Gene Model | MGI Sequence Detail 917157 C57BL/6J ±  kb
transcript NM_001081756 RefSeq | MGI Sequence Detail 7246 C57BL/6  
polypeptide NP_001075225 RefSeq | MGI Sequence Detail 1909 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    10 Sequences
  • InterPro Domains
    IPR032769 Nck-associated protein 5, C-terminal
    IPR026163 Nck-associated protein 5-like
Molecular
Reagents
less
  • All nucleic 32
    Genomic 2
    cDNA 30

    Microarray probesets 3
Other
Accession IDs
less
MGI:2442344
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/21/2023
MGI 6.22 		The Jackson Laboratory