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Nckap5 Gene Detail
Summary
  • Symbol
    Nckap5
  • Name
    NCK-associated protein 5
  • Synonyms
    D130011D22Rik, E030049G20Rik, LOC380609
  • Feature Type
    protein coding gene
  • IDs
    MGI:2686394
    NCBI Gene: 210356
  • Alliance
    genome feature page
  • Transcription Start Sites
    22 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:125841373-126758529 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 54.70 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    25346 from dbSNP Build 142
  • Strain Annotations
    24
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2686394
 protein coding gene Chr1:125841357-126758536 (-)
129S1/SvImJ ENSMUSGG00200054485
 protein coding gene Chr1:123728507-124193371 (-)
129S1/SvImJ ENSMUSG00200007240
 protein coding gene Chr1:123439214-123523888 (-)
A/J ENSMUSGG00195055009
 protein coding gene Chr1:122811292-123278649 (-)
A/J ENSMUSG00195038774
 protein coding gene Chr1:122521955-122606632 (-)
AKR/J ENSMUSG00220047452
 protein coding gene Chr1:122376541-122461229 (-)
AKR/J ENSMUSGG00220054827
 protein coding gene Chr1:122664461-123129282 (-)
BALB/cJ ENSMUSG00180036472
 protein coding gene Chr1:123098667-123183343 (-)
BALB/cJ ENSMUSGG00180055560
 protein coding gene Chr1:123387958-123847498 (-)
C3H/HeJ ENSMUSG00175045194
 protein coding gene Chr1:122803770-122888440 (-)
C3H/HeJ ENSMUSGG00175054828
 protein coding gene Chr1:123093050-123546205 (-)
C57BL/6NJ ENSMUSGG00215055271
 protein coding gene Chr1:123069699-123543129 (-)
C57BL/6NJ ENSMUSG00215043185
 protein coding gene Chr1:122787210-122870156 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014535
 protein coding gene Chr1:117681370-118565720 (-)
CAST/EiJ no annotation
CBA/J ENSMUSGG00210054552
 protein coding gene Chr1:122937790-123408723 (-)
CBA/J ENSMUSG00210027135
 protein coding gene Chr1:122648479-122733157 (-)
DBA/2J ENSMUSG00185002006
 protein coding gene Chr1:127037673-127122342 (-)
DBA/2J ENSMUSGG00185057494
 protein coding gene Chr1:127326981-127791690 (-)
FVB/NJ ENSMUSG00205033765
 protein coding gene Chr1:122091531-122888639 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230001140
 protein coding gene Chr1:126591914-127500319 (-)
NOD/ShiLtJ ENSMUSGG00190054714
 protein coding gene Chr1:122954979-123426248 (-)
NOD/ShiLtJ ENSMUSG00190035836
 protein coding gene Chr1:122669872-122752793 (-)
NZO/HlLtJ ENSMUSG00225004399
 protein coding gene Chr1:130342222-130425175 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010040440
 protein coding gene Chr1:124504302-125427209 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    NCKAP5, NCK associated protein 5
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NCKAP5, NCK associated protein 5
  • Synonyms
    ERIH1, ERIH2, NAP5
  • Links
    NCBI Gene ID: 344148
    UniProt: O14513

  • Chr Location
    2q21.2; chr2:132671788-133674836 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    770
  • Tissues
    21
  • cDNA Data
    30
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 210356 NCBI Gene Model | MGI Sequence Detail 917157 C57BL/6J ±  kb
transcript NM_001081756 RefSeq | MGI Sequence Detail 7246 C57BL/6  
polypeptide NP_001075225 RefSeq | MGI Sequence Detail 1909 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    13 Sequences
  • InterPro Domains
    IPR032769 Nck-associated protein 5, C-terminal
    IPR026163 Nck-associated protein 5-like
  • GlyGen
    E9QAE1 3 sites, 1 O-linked glycan (2 sites)
Molecular
Reagents
less
  • All nucleic 32
    Genomic 2
    cDNA 30

    Microarray probesets 3
Other
Accession IDs
less
MGI:2442344
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory