Igkv16-104 MGI Mouse Gene Detail - MGI:2685913 - immunoglobulin kappa variable 16-104

Symbol

Igkv16-104
Name

immunoglobulin kappa variable 16-104
Synonyms

LOC381778

Feature Type

gene segment
IDs

MGI:2685913
NCBI Gene: 381778
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr6:68402589-68403056 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 6, 31.17 cM
Mapping Data

1 experiment

SNPs within 2kb

43 from dbSNP Build 142
Strain Annotations

17

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685913	gene segment	Chr6:68402559-68403056 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0000125	gene segment	Chr6:68639557-68640054 (+)
A/J	MGP_AJ_G0000116	gene segment	Chr6:65723070-65723567 (+)
AKR/J	MGP_AKRJ_G0000122	gene segment	Chr6:67678634-67679131 (+)
BALB/cJ	MGP_BALBcJ_G0000111	gene segment	Chr6:66006447-66006944 (+)
C3H/HeJ	MGP_C3HHeJ_G0000140	gene segment	Chr6:116496343-116496840 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0000164	gene segment	Chr6:70292108-70292605 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	MGP_CASTEiJ_G0000122	gene segment	Chr6:68029680-68030180 (+)
CBA/J	MGP_CBAJ_G0000116	gene segment	Chr6:73069357-73069854 (+)
DBA/2J	MGP_DBA2J_G0000111	gene segment	Chr6:65321433-65321930 (+)
FVB/NJ	MGP_FVBNJ_G0000111	gene segment	Chr6:64776685-64777182 (+)
LP/J	MGP_LPJ_G0000128	gene segment	Chr6:68455478-68455975 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0000123	gene segment	Chr6:76815643-76816143 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0000148	gene segment	Chr6:67746959-67747459 (+)
PWK/PhJ	MGP_PWKPhJ_G0000104	gene segment	Chr6:64276024-64276524 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0000081	gene segment	Chr6:67141399-67141896 (+)
WSB/EiJ	MGP_WSBEiJ_G0000121	gene segment	Chr6:68070012-68070509 (+)

Human Ortholog

IGKV1-33, immunoglobulin kappa variable 1-33

Vertebrate Orthologs

5

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

IGKV1-33, immunoglobulin kappa variable 1-33
Synonyms

IGKV133, O18
Links

HGNC:5737

NCBI Gene ID: 28933
Chr Location

2p11.2; chr2:89268001-89268506 (-) GRCh38

Human Ortholog

IGKV1-37, immunoglobulin kappa variable 1-37 (non-functional)
Synonyms

IGKV137, O14
Links

HGNC:5739

NCBI Gene ID: 28931

UniProt: A0A075B6S9
Chr Location

2p11.2; chr2:89297264-89297785 (-) GRCh38

Human Ortholog

IGKV1D-33, immunoglobulin kappa variable 1D-33
Synonyms

IGKV1D33, O8
Links

HGNC:5753

NCBI Gene ID: 28896

UniProt: P01593
Chr Location

2p11.2; chr2:89913982-89914545 (+) GRCh38

Human Ortholog

IGKV1D-37, immunoglobulin kappa variable 1D-37 (non-functional)
Synonyms

IGKV1D37, O4
Links

HGNC:5755

NCBI Gene ID: 28894

UniProt: P0DSN7
Chr Location

2p11.2; chr2:89884740-89885216 (+) GRCh38

Human Ortholog

IGKV1OR2-108, immunoglobulin kappa variable 1/OR2-108 (non-functional)
Synonyms

IGKV1OR2108, IGO1
Links

HGNC:5767

NCBI Gene ID: 28862
Chr Location

2q12-q14; chr2:113406396-113406872 (+) GRCh38

MGI Vertebrate Homology

Igkv16-104 stringent orthology
5 human;1 mouse
HCOP

vertebrate homology predictions: IGKV1-33, IGKV1-37, IGKV1D-33, IGKV1D-37, IGKV1OR2-108
Gene Tree

Igkv16-104

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Incidental Mutations

APF
Find Mice (IMSR)

4 strains or lines available

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All GO Annotations

3
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

2

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

28
RefSeq

2
UniProt

1

Ensembl

ENSMUSG00000076522 (Evidence)
NCBI Gene

381778

			Length	Strain/Species	Flank
genomic	381778	NCBI Gene Model \| MGI Sequence Detail	468	C57BL/6J	± kb
transcript	M19911	GenBank \| ENA \| DDBJ \| MGI Sequence Detail	421	BALB/c
polypeptide	A0A0B4J1I1	UniProt \| EBI \| MGI Sequence Detail	116	Not Applicable

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UniProt

1 Sequence
InterPro Domains

IPR007110 Immunoglobulin-like domain

IPR036179 Immunoglobulin-like domain superfamily

IPR013783 Immunoglobulin-like fold

IPR003599 Immunoglobulin subtype

IPR013106 Immunoglobulin V-set domain

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All nucleic 2

cDNA 2

Microarray probesets 1

Summaries

All 13

Gene Ontology 1
Earliest

J:35042 Kofler R, et al., Molecular analysis of the murine lupus-associated anti-self response: involvement of a large number of heavy and light chain variable region genes. Eur J Immunol. 1987 Jan;17(1):91-5
Latest

J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61

TSS for Igkv16-104:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr56923	Chr6:68402551-68402568 (+)	-29 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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