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Lrrc43 Gene Detail
Summary
  • Symbol
    Lrrc43
  • Name
    leucine rich repeat containing 43
  • Synonyms
    LOC381741
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685907
    NCBI Gene: 381741
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:123627368-123646268 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 63.01 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    552 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685907
 protein coding gene Chr5:123627349-123646268 (+)
129S1/SvImJ ENSMUSG00200023620
 protein coding gene Chr5:117349003-117367644 (+)
A/J ENSMUSG00195011691
 protein coding gene Chr5:116870423-116889090 (+)
AKR/J ENSMUSG00220035153
 protein coding gene Chr5:116383039-116402064 (+)
BALB/cJ ENSMUSG00180030850
 protein coding gene Chr5:116985399-117004045 (+)
C3H/HeJ ENSMUSG00175028707
 protein coding gene Chr5:119002874-119021883 (+)
C57BL/6NJ ENSMUSG00215024398
 protein coding gene Chr5:117035703-117054653 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027727
 protein coding gene Chr5:116498729-116519586 (+)
CAST/EiJ ENSTCUG00005035900
 protein coding gene Chr5:116291042-116310199 (+)
CBA/J ENSMUSG00210009190
 protein coding gene Chr5:117753627-117772632 (+)
DBA/2J ENSMUSG00185052010
 protein coding gene Chr5:120804878-120823885 (+)
FVB/NJ ENSMUSG00205039175
 protein coding gene Chr5:116665529-116684486 (+)
JF1/MsJ ENSUMUG00000014349
 protein coding gene Chr5:123668794-123688153 (+)
LP/J ENSMUSG00230043687
 protein coding gene Chr5:124870957-124889599 (+)
NOD/ShiLtJ ENSMUSG00190035614
 protein coding gene Chr5:116679280-116698285 (+)
NZO/HlLtJ ENSMUSG00225013011
 protein coding gene Chr5:132568579-132587514 (+)
PWK/PhJ ENSLUMG00010037261
 protein coding gene Chr5:115561157-115580262 (+)
SPRET/EiJ ENSMSPG00010041778
 protein coding gene Chr5:118869242-118888012 (+)
WSB/EiJ ENSIUOG00005014247
 protein coding gene Chr5:119369380-119388017 (+)



Homology
more
  • Human Ortholog
    LRRC43, leucine rich repeat containing 43
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC43, leucine rich repeat containing 43
  • Links
    NCBI Gene ID: 254050
    UniProt: Q8N309

  • Chr Location
    12q24.31; chr12:122167719-122203471 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000063409 Ensembl Gene Model | MGI Sequence Detail 18901 C57BL/6J ±  kb
transcript ENSMUST00000094327 Ensembl | MGI Sequence Detail 2046 Not Applicable  
polypeptide ENSMUSP00000091885 Ensembl | MGI Sequence Detail 667 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000032491 leucine-rich repeat-containing protein 43
    (term hierarchy)
  • PDB
    9IJJ
  • InterPro Domains
    IPR050576 Ciliary and flagellar integrity-associated protein
    IPR060203 Leucine-rich repeat-containing protein 43, C-terminal domain
    IPR060201 Leucine-rich repeat-containing protein 43, N-terminal domain
    IPR032675 Leucine-rich repeat domain superfamily
  • GlyGen
    Q3V0L5 1 site
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 1
References
more
  • Summaries
    All 24
    Phenotypes 8
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory