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Ccdc180 Gene Detail
Summary
  • Symbol
    Ccdc180
  • Name
    coiled-coil domain containing 180
  • Synonyms
    E230008N13Rik, LOC381522
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685871
    NCBI Gene: 381522
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:45890303-45950774 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 24.42 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1759 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685871
 protein coding gene Chr4:45890303-45950774 (+)
129S1/SvImJ ENSMUSG00200002958
 protein coding gene Chr4:41945115-42005812 (+)
A/J ENSMUSG00195006270
 protein coding gene Chr4:42398751-42459549 (+)
AKR/J ENSMUSG00220002431
 protein coding gene Chr4:42089724-42150420 (+)
BALB/cJ ENSMUSG00180027057
 protein coding gene Chr4:41985438-42046222 (+)
C3H/HeJ ENSMUSG00175020276
 protein coding gene Chr4:42134940-42195726 (+)
C57BL/6NJ ENSMUSG00215013164
 protein coding gene Chr4:41912948-41973655 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025978
 protein coding gene Chr4:39950486-40012284 (+)
CAST/EiJ ENSTCUG00005035067
 protein coding gene Chr4:42154420-42215487 (+)
CBA/J ENSMUSG00210019004
 protein coding gene Chr4:41821912-41882669 (+)
DBA/2J ENSMUSG00185030423
 protein coding gene Chr4:42185305-42246068 (+)
FVB/NJ ENSMUSG00205017347
 protein coding gene Chr4:41480807-41541500 (+)
JF1/MsJ ENSUMUG00000034229
 protein coding gene Chr4:42405247-42467090 (+)
LP/J ENSMUSG00230042229
 protein coding gene Chr4:45746133-45806829 (+)
NOD/ShiLtJ ENSMUSG00190022291
 protein coding gene Chr4:42047831-42108523 (+)
NZO/HlLtJ ENSMUSG00225006693
 protein coding gene Chr4:50340606-50401304 (+)
PWK/PhJ ENSLUMG00010011872
 protein coding gene Chr4:41417234-41478857 (+)
SPRET/EiJ ENSMSPG00010008226
 protein coding gene Chr4:42327092-42388367 (+)
WSB/EiJ ENSIUOG00005004068
 protein coding gene Chr4:41797968-41858815 (+)



Homology
more
  • Human Ortholog
    CCDC180, coiled-coil domain containing 180
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC180, coiled-coil domain containing 180
  • Synonyms
    C9orf174, CFAP76, FAP76
  • Links
    NCBI Gene ID: 100499483
    UniProt: Q9P1Z9

  • Chr Location
    9q22.33; chr9:97307304-97378751 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    666
  • Tissues
    12
  • cDNA Data
    5
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 381522 NCBI Gene Model | MGI Sequence Detail 60472 C57BL/6J ±  kb
    transcript NM_198660 RefSeq | MGI Sequence Detail 5081 C57BL/6  
    polypeptide NP_941062 RefSeq | MGI Sequence Detail 1664 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • PDB
      9IJJ
    • InterPro Domains
      IPR028089 Domain of unknown function DUF4455
      IPR027914 Domain of unknown function DUF4456
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 1
    References
    more
    • Summaries
      All 24
      Developmental Gene Expression 2
      Phenotypes 7
    • Earliest
      J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory