About   Help   FAQ
Ajm1 Gene Detail
Summary
  • Symbol
    Ajm1
  • Name
    apical junction component 1
  • Synonyms
    Gm996, LOC381353
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685842
    NCBI Gene: 381353
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:25465428-25471760 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 17.44 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    124 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685842
 protein coding gene Chr2:25465428-25471769 (-)
129S1/SvImJ ENSMUSG00200048645
 protein coding gene Chr2:22453975-22454427 (-)
A/J ENSMUSG00195041933
 protein coding gene Chr2:22544050-22544502 (-)
AKR/J ENSMUSG00220048360
 protein coding gene Chr2:22661881-22662333 (-)
BALB/cJ ENSMUSG00180054272
 protein coding gene Chr2:22555634-22556086 (-)
C3H/HeJ ENSMUSG00175046608
 protein coding gene Chr2:22519783-22520235 (-)
C57BL/6NJ ENSMUSG00215042025
 protein coding gene Chr2:22578524-22578976 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023285
 protein coding gene Chr2:21474545-21480934 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210016634
 protein coding gene Chr2:22558761-22559213 (-)
DBA/2J ENSMUSG00185051042
 protein coding gene Chr2:22458238-22458690 (-)
FVB/NJ ENSMUSG00205049470
 protein coding gene Chr2:22312598-22313050 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230040521
 protein coding gene Chr2:24389962-24390414 (-)
NOD/ShiLtJ ENSMUSG00190049933
 protein coding gene Chr2:22549102-22549554 (-)
NZO/HlLtJ ENSMUSG00225009018
 protein coding gene Chr2:32140393-32140845 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    AJM1, apical junction component 1 homolog
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AJM1, apical junction component 1 homolog
  • Synonyms
    ajm-1, C9orf172
  • Links
    NCBI Gene ID: 389813
    UniProt: C9J069

  • Chr Location
    9q34.3; chr9:136842478-136848801 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 381353 NCBI Gene Model | MGI Sequence Detail 6333 C57BL/6J ±  kb
    transcript NM_001005424 RefSeq | MGI Sequence Detail 4901 C57BL/6  
    polypeptide A2AJA9 UniProt | EBI | MGI Sequence Detail 974 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000059727 apical junction component 1 homolog
      (term hierarchy)
    • InterPro Domains
      IPR038825 Apical junction component
      IPR060583 Apical junction component 1, C-terminal domain
      IPR058586 Apical junction molecule ajm1, alpha/beta domain
    • GlyGen
      A2AJA9 9 sites, 1 O-linked glycan (5 sites)
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:6156100
    References
    more
    • Summaries
      All 25
      Gene Ontology 4
      Phenotypes 3
    • Earliest
      J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
    • Latest
      J:385281 Del Mar Masdeu M, et al., Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry. Oncotarget. 2017 Nov 24;8(60):101146-101157
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory