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Fam186a Gene Detail
Summary
  • Symbol
    Fam186a
  • Name
    family with sequence similarity 186, member A
  • Synonyms
    1700030F18Rik, LOC380973
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685766
    NCBI Gene: 72277
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:99816229-99864942 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 56.13 cM, cytoband F3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1124 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685766
 protein coding gene Chr15:99816226-99864974 (-)
129S1/SvImJ ENSMUSG00200050465
 protein coding gene Chr15:97018451-97067860 (-)
A/J ENSMUSG00195037352
 protein coding gene Chr15:96885460-96943207 (-)
AKR/J ENSMUSG00220044001
 protein coding gene Chr15:96892748-96941509 (-)
BALB/cJ ENSMUSG00180036841
 protein coding gene Chr15:96795207-96843832 (-)
C3H/HeJ ENSMUSG00175039141
 protein coding gene Chr15:97065471-97123211 (-)
C57BL/6NJ ENSMUSG00215050201
 protein coding gene Chr15:96854612-96903350 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020280
 protein coding gene Chr15:93621381-93633742 (-)
CAST/EiJ ENSTCUG00005045943
 protein coding gene Chr15:96326902-96376192 (-)
CBA/J ENSMUSG00210026582
 protein coding gene Chr15:96852117-96900736 (-)
DBA/2J ENSMUSG00185036123
 protein coding gene Chr15:96899130-96947872 (-)
FVB/NJ ENSMUSG00205028457
 protein coding gene Chr15:96603614-96652359 (-)
JF1/MsJ ENSUMUG00000046310
 protein coding gene Chr15:96351706-96401274 (-)
LP/J ENSMUSG00230038445
 protein coding gene Chr15:100241815-100291227 (-)
NOD/ShiLtJ ENSMUSG00190045403
 protein coding gene Chr15:96869146-96917895 (-)
NZO/HlLtJ ENSMUSG00225042892
 protein coding gene Chr15:100491495-100540235 (-)
PWK/PhJ ENSLUMG00010046109
 protein coding gene Chr15:96574028-96622803 (-)
SPRET/EiJ ENSMSPG00010047216
 protein coding gene Chr15:98376374-98424774 (-)
WSB/EiJ ENSIUOG00005032193
 protein coding gene Chr15:96979755-97028498 (-)



Homology
more
  • Human Ortholog
    FAM186A, family with sequence similarity 186 member A
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM186A, family with sequence similarity 186 member A
  • Links
    NCBI Gene ID: 121006
    UniProt: A6NE01

  • Chr Location
    12q13.12; chr12:50326230-50396622 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    25 phenotype references
  • All Mutations and Alleles
    22
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    18
  • Radiation induced
    2
  • Genomic Mutations
    3 involving Fam186a
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    100 strains or lines available
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045350 Ensembl Gene Model | MGI Sequence Detail 48714 C57BL/6J ±  kb
transcript ENSMUST00000100209 Ensembl | MGI Sequence Detail 9320 Not Applicable  
polypeptide ENSMUSP00000097783 Ensembl | MGI Sequence Detail 3035 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 4
Other
Accession IDs
less
MGI:1919527
References
more
  • Summaries
    All 47
    Diseases 1
    Phenotypes 25
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory