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Ldc1 Gene Detail
Summary
  • Symbol
    Ldc1
  • Name
    leucine decarboxylase 1
  • Synonyms
    Gm853, LOC332942
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685699
    NCBI Gene: 332942
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:130102902-130116194 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 63.43 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    80 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685699
 protein coding gene Chr4:130102816-130116221 (-)
129S1/SvImJ ENSMUSG00200019264
 protein coding gene Chr4:123545548-123558817 (-)
A/J ENSMUSG00195039332
 protein coding gene Chr4:124879009-124892300 (-)
AKR/J ENSMUSG00220035898
 protein coding gene Chr4:123870794-123884096 (-)
BALB/cJ ENSMUSG00180043841
 protein coding gene Chr4:122512637-122525925 (-)
C3H/HeJ ENSMUSG00175038695
 protein coding gene Chr4:123525182-123538481 (-)
C57BL/6NJ ENSMUSG00215048356
 protein coding gene Chr4:125029064-125042357 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026542
 protein coding gene Chr4:120017525-120030877 (-)
CAST/EiJ ENSTCUG00005043789
 protein coding gene Chr4:124411477-124424764 (-)
CBA/J ENSMUSG00210052930
 protein coding gene Chr4:123154184-123167479 (-)
DBA/2J ENSMUSG00185050790
 protein coding gene Chr4:124686571-124699866 (-)
FVB/NJ ENSMUSG00205042121
 protein coding gene Chr4:122912535-122925655 (-)
JF1/MsJ ENSUMUG00000011689
 protein coding gene Chr4:125343507-125355525 (-)
LP/J ENSMUSG00230032741
 protein coding gene Chr4:128484209-128497488 (-)
NOD/ShiLtJ ENSMUSG00190030399
 protein coding gene Chr4:122919026-122932321 (-)
NZO/HlLtJ ENSMUSG00225026308
 protein coding gene Chr4:134397452-134410746 (-)
PWK/PhJ ENSLUMG00010048088
 protein coding gene Chr4:122374682-122386700 (-)
SPRET/EiJ ENSMSPG00010036370
 protein coding gene Chr4:124437571-124450358 (-)
WSB/EiJ ENSIUOG00005037271
 protein coding gene Chr4:122780404-122793676 (-)



Homology
more
  • Human Ortholog
    LDC1P, leucine decarboxylase 1, pseudogene
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LDC1P, leucine decarboxylase 1, pseudogene
  • Synonyms
    LINC01225, SEELA1
  • Links
    NCBI Gene ID: 149086

  • Chr Location
    1p35.2; chr1:31500085-31509648 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023120 Ensembl Gene Model | MGI Sequence Detail 13293 C57BL/6J ±  kb
transcript ENSMUST00000023884 Ensembl | MGI Sequence Detail 2314 Not Applicable  
polypeptide ENSMUSP00000023884 Ensembl | MGI Sequence Detail 425 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR009006 Alanine racemase/group IV decarboxylase, C-terminal
    IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site
    IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal
    IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site
    IPR000183 Ornithine/DAP/Arg decarboxylase
    IPR002433 Ornithine decarboxylase
    IPR029066 PLP-binding barrel
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 1
Other
Accession IDs
less
MGI:3841243, MGI:6304470
References
more
  • Summaries
    All 21
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:255630 Lambertos A, et al., The mouse Gm853 gene encodes a novel enzyme: Leucine decarboxylase. Biochim Biophys Acta. 2017 Nov 4;1862(3):365-376
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory