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Thsd7a Gene Detail
Summary
  • Symbol
    Thsd7a
  • Name
    thrombospondin, type I, domain containing 7A
  • Synonyms
    LOC330267
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685683
    NCBI Gene: 330267
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:12311607-12749252 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 5.31 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2692 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685683
 protein coding gene Chr6:12311607-12749409 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030456
 protein coding gene Chr6:9340569-9783922 (-)
A/J MGP_AJ_G0030429
 protein coding gene Chr6:9011489-9433605 (-)
AKR/J MGP_AKRJ_G0030356
 protein coding gene Chr6:9325551-9757860 (-)
BALB/cJ MGP_BALBcJ_G0030438
 protein coding gene Chr6:8998505-9430302 (-)
C3H/HeJ MGP_C3HHeJ_G0030152
 protein coding gene Chr6:9211558-9666382 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030893
 protein coding gene Chr6:9736854-10188488 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028104
 protein coding gene Chr6:8303977-8701014 (-)
CAST/EiJ MGP_CASTEiJ_G0029554
 protein coding gene Chr6:9085494-9521371 (-)
CBA/J MGP_CBAJ_G0030130
 protein coding gene Chr6:9889946-10388837 (-)
DBA/2J MGP_DBA2J_G0030274
 protein coding gene Chr6:8937402-9366740 (-)
FVB/NJ MGP_FVBNJ_G0030228
 protein coding gene Chr6:8850147-9271272 (-)
LP/J MGP_LPJ_G0030361
 protein coding gene Chr6:9306500-9750035 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030264
 protein coding gene Chr6:10550155-11101399 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030923
 protein coding gene Chr6:9193963-9641020 (-)
PWK/PhJ MGP_PWKPhJ_G0029268
 protein coding gene Chr6:8687518-9098241 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029104
 protein coding gene Chr6:9144352-9572545 (-)
WSB/EiJ MGP_WSBEiJ_G0029630
 protein coding gene Chr6:9125177-9559274 (-)



Homology
more
  • Human Ortholog
    THSD7A, thrombospondin type 1 domain containing 7A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    THSD7A, thrombospondin type 1 domain containing 7A
  • Links
    NCBI Gene ID: 221981
    neXtProt AC: NX_Q9UPZ6
    UniProt: Q9UPZ6

  • Chr Location
    7p21.3; chr7:11370365-11832198 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
DNA-templated transcription
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1197
  • Tissues
    85
  • cDNA Data
    10
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 330267 NCBI Gene Model | MGI Sequence Detail 437646 C57BL/6J ±  kb
    transcript NM_001164805 RefSeq | MGI Sequence Detail 11019 C57BL/6  
    polypeptide Q69ZU6 UniProt | EBI | MGI Sequence Detail 1645 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 10
      Primer pair 2

      Microarray probesets 2
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 7
      Gene Ontology 4
      Phenotypes 8
    • Earliest
      J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
    • Latest
      J:336253 Seifert L, et al., The classical pathway triggers pathogenic complement activation in membranous nephropathy. Nat Commun. 2023 Jan 28;14(1):473
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/21/2023
    MGI 6.22     		The Jackson Laboratory