Wmp Gene Detail

Summary

• Symbol
  Wmp
• Name
  WAVE homology in membrane protrusions
• Synonyms
  Gm732, Whimp

• Feature Type
  protein coding gene
• IDs
  MGI:2685578
  NCBI Gene: 213450
• Alliance
  genome feature page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  ChrX:106989341-106992042 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome X, 47.66 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  142 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685578	protein coding gene	ChrX:106989341-106992071 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0036018	protein coding gene	ChrX:104804987-104807717 (-)
A/J	MGP_AJ_G0035997	protein coding gene	ChrX:104614742-104617476 (-)
AKR/J	MGP_AKRJ_G0035916	protein coding gene	ChrX:107922228-107924958 (-)
BALB/cJ	MGP_BALBcJ_G0035988	protein coding gene	ChrX:103366004-103368734 (-)
C3H/HeJ	MGP_C3HHeJ_G0035694	protein coding gene	ChrX:105261082-105263812 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0036514	protein coding gene	ChrX:107831590-107834320 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0033342	protein coding gene	ChrX:101827860-101830593 (-)
CAST/EiJ	MGP_CASTEiJ_G0034981	protein coding gene	ChrX:89340048-89342779 (-)
CBA/J	MGP_CBAJ_G0035670	protein coding gene	ChrX:111218079-111220809 (-)
DBA/2J	MGP_DBA2J_G0035824	protein coding gene	ChrX:103841496-103844226 (-)
FVB/NJ	MGP_FVBNJ_G0035764	protein coding gene	ChrX:103203918-103206648 (-)
LP/J	MGP_LPJ_G0035916	protein coding gene	ChrX:105774103-105776833 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0035795	protein coding gene	ChrX:116085557-116088287 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0036541	protein coding gene	ChrX:104345243-104347973 (-)
PWK/PhJ	MGP_PWKPhJ_G0034677	protein coding gene	ChrX:86863717-86866447 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0034506	protein coding gene	ChrX:90167914-90170633 (-)
WSB/EiJ	MGP_WSBEiJ_G0035119	protein coding gene	ChrX:103127748-103130478 (-)

Homology

• MGI Vertebrate Homology
  Wmp stringent orthology
  1 mouse;1 rat
  
• Gene Tree
  Wmp
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Incidental Mutations
  APF
• Find Mice (IMSR)
  2 strains or lines available

Expression

• Assay Results
  706
• cDNA Data
  7

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  33
• RefSeq
  2
• UniProt
  3
• CCDS
  CCDS30352.1

• Ensembl
  ENSMUSG00000073006 (Evidence)
• NCBI Gene
  213450

Representative Sequences			Length	Strain/Species
genomic	213450	NCBI Gene Model | MGI Sequence Detail	2702	C57BL/6J
transcript	NM_001033252	RefSeq | MGI Sequence Detail	1661	C57BL/6
polypeptide	NP_001028424	RefSeq | MGI Sequence Detail	516	C57BL/6

Protein
Information

• UniProt
  3 Sequences
• InterPro Domains
  IPR003124 WH2 domain

Molecular
Reagents

• All nucleic 7

  cDNA 7

  
  

  Microarray probesets 2

Other
Accession IDs

MGI:6438183

References

• Summaries
  All 16

  Phenotypes 2
• Earliest
  J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
• Latest
  J:289916 Kabrawala S, et al., WHIMP links the actin nucleation machinery to Src-family kinase signaling during protrusion and motility. PLoS Genet. 2020 Mar;16(3):e1008694

TSS for Wmp:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr164045	ChrX:106992038-106992049 (-)	-2 bp