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Lkaaear1 Gene Detail
Summary
  • Symbol
    Lkaaear1
  • Name
    LKAAEAR motif containing 1 (IKAAEAR murine motif)
  • Synonyms
    4930526D03Rik, LOC277496
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685538
    NCBI Gene: 277496
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:181338586-181340235 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 103.73 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    88 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685538
protein coding gene Chr2:181338586-181340235 (-)
129S1/SvImJ ENSMUSG00200002111
protein coding gene Chr2:177361387-177363048 (-)
A/J ENSMUSG00195001027
protein coding gene Chr2:177592126-177593775 (-)
AKR/J ENSMUSG00220000077
protein coding gene Chr2:175270788-175272437 (-)
BALB/cJ ENSMUSG00180000684
protein coding gene Chr2:175402349-175403998 (-)
C3H/HeJ ENSMUSG00175004287
protein coding gene Chr2:176552674-176554323 (-)
C57BL/6NJ ENSMUSG00215002534
protein coding gene Chr2:175500709-175502358 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024819
protein coding gene Chr2:171234639-171237145 (-)
CAST/EiJ ENSTCUG00005000528
protein coding gene Chr2:174851635-174853290 (-)
CBA/J ENSMUSG00210001411
protein coding gene Chr2:175879177-175880838 (-)
DBA/2J ENSMUSG00185020660
protein coding gene Chr2:177112134-177113783 (-)
FVB/NJ ENSMUSG00205002041
protein coding gene Chr2:175930785-175932434 (-)
JF1/MsJ ENSUMUG00000012519
protein coding gene Chr2:178305904-178307547 (-)
LP/J ENSMUSG00230023778
protein coding gene Chr2:179012283-179013944 (-)
NOD/ShiLtJ ENSMUSG00190015185
protein coding gene Chr2:175420807-175422468 (-)
NZO/HlLtJ ENSMUSG00225005991
protein coding gene Chr2:187094355-187096004 (-)
PWK/PhJ ENSLUMG00010000119
protein coding gene Chr2:175725654-175727303 (-)
SPRET/EiJ ENSMSPG00010003736
protein coding gene Chr2:178196570-178198228 (-)
WSB/EiJ ENSIUOG00005000174
protein coding gene Chr2:175446254-175447903 (-)



Homology
more
  • Human Ortholog
    LKAAEAR1, LKAAEAR motif containing 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LKAAEAR1, LKAAEAR motif containing 1
  • Synonyms
    C20orf201
  • Links
    NCBI Gene ID: 198437
    UniProt: Q8TD35

  • Chr Location
    20q13.33; chr20:64083376-64084967 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 277496 NCBI Gene Model | MGI Sequence Detail 1650 C57BL/6J ±  kb
    transcript NM_001378943 RefSeq | MGI Sequence Detail 791 C57BL/6  
    polypeptide Q8BIG2 UniProt | EBI | MGI Sequence Detail 198 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 7

      Microarray probesets 2
    References
    more
    • Summaries
      All 23
      Phenotypes 5
    • Earliest
      J:162220 Magdaleno S, et al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    09/08/2026
    MGI 6.24
    The Jackson Laboratory