Prr22 Gene Detail

Summary

• Symbol
  Prr22
• Name
  proline rich 22
• Synonyms
  Gm546, LOC224908

• Feature Type
  protein coding gene
• IDs
  MGI:2685392
  NCBI Gene: 100504446
• Alliance
  genome feature page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr17:57077276-57079134 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 17, 29.50 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  76 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685392	protein coding gene	Chr17:57077250-57079208 (+)
129S1/SvImJ	ENSMUSG00200016531	protein coding gene	Chr17:52352925-52354783 (+)
A/J	ENSMUSG00195006624	protein coding gene	Chr17:53740655-53742513 (+)
AKR/J	ENSMUSG00220012056	protein coding gene	Chr17:52789987-52791845 (+)
BALB/cJ	ENSMUSG00180005726	protein coding gene	Chr17:53498295-53500153 (+)
C3H/HeJ	ENSMUSG00175007298	protein coding gene	Chr17:52814293-52816151 (+)
C57BL/6NJ	ENSMUSG00215008391	protein coding gene	Chr17:52428452-52430310 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0021790	protein coding gene	Chr17:53359510-53361480 (+)
CAST/EiJ	ENSTCUG00005018850	protein coding gene	Chr17:53544994-53546851 (+)
CBA/J	ENSMUSG00210028121	protein coding gene	Chr17:52581372-52583230 (+)
DBA/2J	ENSMUSG00185007829	protein coding gene	Chr17:55451216-55453074 (+)
FVB/NJ	ENSMUSG00205006664	protein coding gene	Chr17:53128631-53130489 (+)
JF1/MsJ	ENSUMUG00000032798	protein coding gene	Chr17:55138352-55140208 (+)
LP/J	ENSMUSG00230025742	protein coding gene	Chr17:56430294-56432152 (+)
NOD/ShiLtJ	ENSMUSG00190010644	protein coding gene	Chr17:52583849-52585707 (+)
NZO/HlLtJ	ENSMUSG00225042723	protein coding gene	Chr17:58714397-58716255 (+)
PWK/PhJ	ENSLUMG00010008788	protein coding gene	Chr17:52388895-52390752 (+)
SPRET/EiJ	ENSMSPG00010005439	protein coding gene	Chr17:52706318-52708173 (+)
WSB/EiJ	ENSIUOG00005021821	protein coding gene	Chr17:53489644-53491502 (+)

Homology

• Human Ortholog
  PRR22, proline rich 22

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  PRR22, proline rich 22
  
• Links
  HGNC:28354

  NCBI Gene ID: 163154

  UniProt: Q8IZ63

  
  
• Chr Location
  19p13.3; chr19:5782960-5784746 (-)  GRCh38

---

• MGI Vertebrate Homology
  Prr22 stringent orthology
  1 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: PRR22
• Gene Tree
  Prr22
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  14 strains or lines available

Gene Ontology
(GO)
Classifications

Expression

• Assay Results
  597
• cDNA Data
  4

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  29
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS57104.1

• Ensembl
  ENSMUSG00000090273 (Evidence)
• NCBI Gene
  100504446

Representative Sequences			Length	Strain/Species
genomic	100504446	NCBI Gene Model | MGI Sequence Detail	1859	C57BL/6J
transcript	NM_001195673	RefSeq | MGI Sequence Detail	1350	C57BL/6
polypeptide	NP_001182602	RefSeq | MGI Sequence Detail	422	C57BL/6

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR031535 Proline-rich protein 22
• GlyGen
  F6TNE3 1 site

Molecular
Reagents

• All nucleic 4

  cDNA 4

  
  

  Microarray probesets 1

References

• Summaries
  All 14

  Phenotypes 1
• Earliest
  J:23000 MGD Nomenclature Committee, Nomenclature Committee Use. 1995-02-14;
• Latest
  J:389486 Mouse Genome Informatics and Ensembl Genome Database Project, MGI Strain Genome Feature and Gene Model Load from Ensembl. Database Release. 2026;

TSS for Prr22:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr145342	Chr17:57077258-57077305 (+)	6 bp