Fam83b MGI Mouse Gene Detail - MGI:2685362 - family with sequence similarity 83, member B

Symbol

Fam83b
Name

family with sequence similarity 83, member B
Synonyms

C530008M07Rik

Feature Type

protein coding gene
IDs

MGI:2685362
NCBI Gene: 208994
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr9:76397336-76474398 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 9, 42.67 cM
Mapping Data

2 experiments

SNPs within 2kb

401 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685362	protein coding gene	Chr9:76394742-76474398 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0035049	protein coding gene	Chr9:76879800-76963596 (-)
A/J	MGP_AJ_G0035030	protein coding gene	Chr9:74187298-74265143 (-)
AKR/J	MGP_AKRJ_G0034959	protein coding gene	Chr9:75954674-76033632 (-)
BALB/cJ	MGP_BALBcJ_G0035022	protein coding gene	Chr9:73869369-73948069 (-)
C3H/HeJ	MGP_C3HHeJ_G0034731	protein coding gene	Chr9:76435688-76518859 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0035540	protein coding gene	Chr9:78917113-79004002 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0032451	protein coding gene	Chr9:73492334-73567808 (-)
CAST/EiJ	MGP_CASTEiJ_G0034053	protein coding gene	Chr9:76786144-76843216 (-)
CBA/J	MGP_CBAJ_G0034703	protein coding gene	Chr9:81651610-81742880 (-)
DBA/2J	MGP_DBA2J_G0034863	protein coding gene	Chr9:73859047-73939014 (-)
FVB/NJ	MGP_FVBNJ_G0034805	protein coding gene	Chr9:73137945-73215816 (-)
LP/J	MGP_LPJ_G0034944	protein coding gene	Chr9:77110826-77198020 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0034846	protein coding gene	Chr9:82778359-82869580 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0035563	protein coding gene	Chr9:76126535-76207064 (-)
PWK/PhJ	MGP_PWKPhJ_G0033757	protein coding gene	Chr9:74112303-74191060 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0033590	protein coding gene	Chr9:76362279-76440385 (-)
WSB/EiJ	MGP_WSBEiJ_G0034165	protein coding gene	Chr9:76049081-76132942 (-)

Human Ortholog

FAM83B, family with sequence similarity 83 member B

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

FAM83B, family with sequence similarity 83 member B
Synonyms

C6orf143
Links

HGNC:21357

NCBI Gene ID: 222584

neXtProt AC: NX_Q5T0W9

UniProt: Q5T0W9
Chr Location

6p12.1; chr6:54846203-54945099 (+) GRCh38

MGI Vertebrate Homology

Fam83b stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: FAM83B
Gene Tree

Fam83b

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Phenotype Summary

8 phenotypes from 1 allele in 1 genetic background
14 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

9
Chemically induced (other)

1
Endonuclease-mediated

2
Gene trapped

2
Radiation induced

1
Targeted

3
Genomic Mutations

2 involving Fam83b
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

51 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

33
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

757
Tissues

4
cDNA Data

16
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase fam83b

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All Sequences

38
RefSeq

8
UniProt

1
CCDS

CCDS40695.1

Ensembl

ENSMUSG00000032358 (Evidence)
NCBI Gene

208994

			Length	Strain/Species	Flank
genomic	ENSMUSG00000032358	Ensembl Gene Model \| MGI Sequence Detail	77063	C57BL/6J	± kb
transcript	ENSMUST00000183437	Ensembl \| MGI Sequence Detail	3879	Not Applicable
polypeptide	ENSMUSP00000139354	Ensembl \| MGI Sequence Detail	1012	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000031474 protein FAM83B

(term hierarchy)
InterPro Domains

IPR012461 FAM83, N-terminal

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All nucleic 16

cDNA 16

Microarray probesets 1

Summaries

All 35

Developmental Gene Expression 1

Gene Ontology 5

Phenotypes 14
Earliest

J:12013 Russell LB, Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations. Mutat Res. 1971 Jan;11(1):107-23
Latest

J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

TSS for Fam83b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr90579	Chr9:76474408-76474413 (-)	-13 bp
Tssr90578	Chr9:76474374-76474405 (-)	8 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23