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Otol1 Gene Detail
Summary
  • Symbol
    Otol1
  • Name
    otolin 1
  • Synonyms
    Gm414, LOC229389
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685260
    NCBI Gene: 229389
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:69914946-69936041 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 32.41 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    623 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685260
 protein coding gene Chr3:69914946-69936041 (+)
129S1/SvImJ ENSMUSG00200001129
 protein coding gene Chr3:66669577-66697308 (+)
A/J ENSMUSG00195026549
 protein coding gene Chr3:66785646-66806708 (+)
AKR/J ENSMUSG00220024277
 protein coding gene Chr3:66789248-66810410 (+)
BALB/cJ ENSMUSG00180008268
 protein coding gene Chr3:66859729-66880777 (+)
C3H/HeJ ENSMUSG00175003518
 protein coding gene Chr3:66692839-66713893 (+)
C57BL/6NJ ENSMUSG00215006095
 protein coding gene Chr3:67130916-67152012 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025071
 protein coding gene Chr3:63447729-63472203 (+)
CAST/EiJ ENSTCUG00005021865
 protein coding gene Chr3:66303208-66325532 (+)
CBA/J ENSMUSG00210001741
 protein coding gene Chr3:66801524-66822682 (+)
DBA/2J ENSMUSG00185014939
 protein coding gene Chr3:66950099-66971260 (+)
FVB/NJ no annotation
JF1/MsJ ENSUMUG00000000837
 protein coding gene Chr3:66527965-66549748 (+)
LP/J ENSMUSG00230002183
 protein coding gene Chr3:68956333-68984065 (+)
NOD/ShiLtJ ENSMUSG00190003087
 protein coding gene Chr3:67247640-67268842 (+)
NZO/HlLtJ ENSMUSG00225004548
 protein coding gene Chr3:71661636-71682801 (+)
PWK/PhJ ENSLUMG00010014827
 protein coding gene Chr3:66651698-66673406 (+)
SPRET/EiJ ENSMSPG00010007480
 protein coding gene Chr3:67146685-67168569 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    OTOL1, otolin 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OTOL1, otolin 1
  • Synonyms
    C1QTNF15, C1QTNF16
  • Links
    NCBI Gene ID: 131149
    UniProt: A6NHN0

  • Chr Location
    3q26.1; chr3:161496808-161503942 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • Tissues
    56
  • cDNA Data
    3
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 229389 NCBI Gene Model | MGI Sequence Detail 21096 C57BL/6J ±  kb
    transcript NM_001018031 RefSeq | MGI Sequence Detail 2161 C57BL/6  
    polypeptide Q4ZJM7 UniProt | EBI | MGI Sequence Detail 482 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 3
      Primer pair 4
      Antibodies 4

      Microarray probesets 1
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 6
      Diseases 1
      Gene Ontology 6
      Phenotypes 11
    • Earliest
      J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
    • Latest
      J:378075 Fan H, et al., Partial embryo loss caused by disruption of the placental hormone CTRP6 coincides with dNK cell abnormalities during pregnancy. iScience. 2026 Jan 16;29(1):114434
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory