Cdhr18 MGI Mouse Gene Detail - MGI:2685127 - cadherin related family member 18

Symbol

Cdhr18
Name

cadherin related family member 18
Synonyms

Gm281, LOC238939

Feature Type

protein coding gene
IDs

MGI:2685127
NCBI Gene: 238939
Alliance

genome feature page
Transcription Start Sites

3 TSS

Sequence Map

Chr14:8555242-8646046 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 14, 7.07 cM
Mapping Data

1 experiment

SNPs within 2kb

2977 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685127	protein coding gene	Chr14:8555242-8655145 (+)
129S1/SvImJ	ENSMUSG00200025206	protein coding gene	Chr14:5194336-5302198 (+)
A/J	ENSMUSG00195029897	protein coding gene	Chr14:6019343-6125744 (+)
AKR/J	ENSMUSG00220022920	protein coding gene	Chr14:5179476-5285872 (+)
BALB/cJ	ENSMUSG00180022077	protein coding gene	Chr14:5344463-5450835 (+)
C3H/HeJ	ENSMUSG00175008904	protein coding gene	Chr14:5338513-5446394 (+)
C57BL/6NJ	ENSMUSG00215011887	protein coding gene	Chr14:5598295-5698158 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018956	protein coding gene	Chr14:6831571-6939837 (-)
CAST/EiJ	ENSTCUG00005029918	protein coding gene	Chr14:5255693-5361112 (+)
CBA/J	ENSMUSG00210034292	protein coding gene	Chr14:5560809-5668698 (+)
DBA/2J	ENSMUSG00185036344	protein coding gene	Chr14:5566690-5674555 (+)
FVB/NJ	ENSMUSG00205024168	protein coding gene	Chr14:5560556-5661370 (+)
JF1/MsJ	ENSUMUG00000017701	protein coding gene	Chr14:5575037-5682954 (+)
LP/J	ENSMUSG00230006532	protein coding gene	Chr14:6694713-6802591 (+)
NOD/ShiLtJ	ENSMUSG00190026286	protein coding gene	Chr14:5590341-5690198 (+)
NZO/HlLtJ	ENSMUSG00225036724	protein coding gene	Chr14:5991550-6091416 (+)
PWK/PhJ	ENSLUMG00010030454	protein coding gene	Chr14:26901576-27010030 (+)
SPRET/EiJ	ENSMSPG00010002320	protein coding gene	Chr14:5873029-5983091 (+)
WSB/EiJ	ENSIUOG00005024206	protein coding gene	Chr14:5420811-5520036 (+)

Human Ortholog

CDHR18P, cadherin related family member 18, pseudogene

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CDHR18P, cadherin related family member 18, pseudogene
Links

HGNC:53742

NCBI Gene ID: 100130345
Chr Location

3p14.2-p14.1; chr3:63757997-63813637 (-) GRCh38

MGI Vertebrate Homology

Cdhr18 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: CDHR18P
Gene Tree

Cdhr18

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Phenotype Summary

2 phenotype references

All Mutations and Alleles

1
Gene trapped

1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

34 strains or lines available

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All GO Annotations

16
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

597
cDNA Data

1

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

30
RefSeq

5
UniProt

1

Ensembl

ENSMUSG00000084902 (Evidence)
NCBI Gene

238939

			Length	Strain/Species	Flank
genomic	238939	NCBI Gene Model \| MGI Sequence Detail	90805	C57BL/6J	± kb
transcript	NM_001393529	RefSeq \| MGI Sequence Detail	2518	C57BL/6
polypeptide	NP_001380458	RefSeq \| MGI Sequence Detail	818	C57BL/6

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UniProt

1 Sequence
InterPro Domains

IPR039808 Cadherin

IPR002126 Cadherin-like

IPR015919 Cadherin-like superfamily

IPR063847 CDHR3, N-terminal domain
GlyGen

D3Z1Y0 1 site

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All nucleic 1

cDNA 1

Microarray probesets 1

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MGI:7382746

Summaries

All 16

Gene Ontology 4

Phenotypes 2
Earliest

J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22

TSS for Cdhr18:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr127482	Chr14:8555254-8555270 (+)	20 bp
Tssr127481	Chr14:8555285-8555299 (+)	50 bp
Tssr127480	Chr14:8563238-8563281 (+)	8,018 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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