Cdr2l Gene Detail

Summary

• Symbol
  Cdr2l
• Name
  cerebellar degeneration-related protein 2-like
• Synonyms
  D030068L24Rik

• Feature Type
  protein coding gene
• IDs
  MGI:2684867
  NCBI Gene: 237988
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr11:115272742-115286958 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, 80.84 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  42 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2684867	protein coding gene	Chr11:115272700-115286961 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0019383	protein coding gene	Chr11:119402429-119416598 (+)
A/J	MGP_AJ_G0019352	protein coding gene	Chr11:114186688-114201999 (+)
AKR/J	MGP_AKRJ_G0019322	protein coding gene	Chr11:117592772-117609027 (+)
BALB/cJ	MGP_BALBcJ_G0019326	protein coding gene	Chr11:114602503-114616675 (+)
C3H/HeJ	MGP_C3HHeJ_G0019132	protein coding gene	Chr11:117944175-117960199 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0019776	protein coding gene	Chr11:123039130-123054831 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017399	protein coding gene	Chr11:111228311-111242216 (+)
CAST/EiJ	MGP_CASTEiJ_G0018687	protein coding gene	Chr11:119257200-119270352 (+)
CBA/J	MGP_CBAJ_G0019104	protein coding gene	Chr11:127893460-127907759 (+)
DBA/2J	MGP_DBA2J_G0019215	protein coding gene	Chr11:113624267-113639131 (+)
FVB/NJ	MGP_FVBNJ_G0019207	protein coding gene	Chr11:113100387-113114592 (+)
LP/J	MGP_LPJ_G0019285	protein coding gene	Chr11:119782043-119800004 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0019240	protein coding gene	Chr11:127069642-127086888 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019814	protein coding gene	Chr11:118250104-118264958 (+)
PWK/PhJ	MGP_PWKPhJ_G0018451	protein coding gene	Chr11:114905804-114921289 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0018244	protein coding gene	Chr11:117995821-118010500 (+)
WSB/EiJ	MGP_WSBEiJ_G0018739	protein coding gene	Chr11:118198280-118214365 (+)

Homology

• Human Ortholog
  CDR2L, cerebellar degeneration related protein 2 like

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  CDR2L, cerebellar degeneration related protein 2 like
  
• Synonyms
  HUMPPA
• Links
  HGNC:29999

  NCBI Gene ID: 30850

  neXtProt AC: NX_Q86X02

  UniProt: Q86X02

  
  
• Chr Location
  17q25.1; chr17:74987632-75005800 (+)  GRCh38

---

• Alliance of Genome Resources
  Cdr2l stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: CDR2L
• Gene Tree
  Cdr2l
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  2
• Endonuclease-mediated
  1
• Targeted
  1
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  12 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  706
• cDNA Data
  15

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  GEISHA CDR2L
  Xenbase cdr2l
  ZFIN cdr2l

Interactions

• Cdr2l interacts with 226 markers (Mir1a-1, Mir1a-2, Mir7-1, ...) View All

Sequences &
Gene Models

• All Sequences
  37
• RefSeq
  6
• UniProt
  3
• CCDS
  CCDS36371.1

• Ensembl
  ENSMUSG00000050910 (Evidence)
• NCBI Gene
  237988

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000050910	Ensembl Gene Model | MGI Sequence Detail	14217	C57BL/6J
transcript	ENSMUST00000053288	Ensembl | MGI Sequence Detail	3700	Not Applicable
polypeptide	ENSMUSP00000052096	Ensembl | MGI Sequence Detail	465	Not Applicable

Protein
Information

• UniProt
  3 Sequences
• Protein Ontology
  PR:000005285 cerebellar degeneration-related protein 2-like
  (term hierarchy)
• InterPro Domains
  IPR026079 Cerebellar degeneration-related protein 2

Molecular
Reagents

• All nucleic 15

  cDNA 15

  
  

  Microarray probesets 3

References

• Summaries
  All 21

  Gene Ontology 1

  Phenotypes 2
• Earliest
  J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Cdr2l:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr105858	Chr11:115272693-115272725 (+)	-33 bp
Tssr105859	Chr11:115272732-115272759 (+)	4 bp
Tssr105860	Chr11:115285462-115285468 (+)	12,723 bp