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Prss43 Gene Detail
Summary
  • Symbol
    Prss43
  • Name
    serine protease 43
  • Synonyms
    LOC272643, Tessp3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684822
    NCBI Gene: 272643
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:110655758-110660575 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 60.79 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    29 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684822
 protein coding gene Chr9:110655758-110660907 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035358
 protein coding gene Chr9:113013087-113018221 (+)
A/J MGP_AJ_G0035339
 protein coding gene Chr9:108890407-108895561 (+)
AKR/J MGP_AKRJ_G0035270
 protein coding gene Chr9:111597977-111603124 (+)
BALB/cJ MGP_BALBcJ_G0035334
 protein coding gene Chr9:108642738-108647888 (+)
C3H/HeJ MGP_C3HHeJ_G0035042
 protein coding gene Chr9:112106645-112111794 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035856
 protein coding gene Chr9:116105439-116110588 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032742
 protein coding gene Chr9:106108885-106114960 (+)
CAST/EiJ MGP_CASTEiJ_G0034348
 protein coding gene Chr9:111899534-111905214 (+)
CBA/J MGP_CBAJ_G0035009
 protein coding gene Chr9:120404242-120409948 (+)
DBA/2J MGP_DBA2J_G0035168
 protein coding gene Chr9:108353179-108358328 (+)
FVB/NJ MGP_FVBNJ_G0035115
 protein coding gene Chr9:107185663-107192528 (+)
LP/J MGP_LPJ_G0035247
 protein coding gene Chr9:113302239-113307319 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035155
 protein coding gene Chr9:121726736-121731881 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035876
 protein coding gene Chr9:111944013-111949161 (+)
PWK/PhJ MGP_PWKPhJ_G0034055
 protein coding gene Chr9:108601887-108608141 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033890
 protein coding gene Chr9:112025057-112030630 (+)
WSB/EiJ MGP_WSBEiJ_G0034469
 protein coding gene Chr9:111808960-111814674 (+)



Homology
more
  • Human Ortholog
    PRSS43P, serine protease 43, pseudogene
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRSS43P, serine protease 43, pseudogene
  • Synonyms
    PRSS43, TESSP3
  • Links
    NCBI Gene ID: 100288960

  • Chr Location
    chr3:46753043-46756855 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    737
  • Tissues
    5
  • cDNA Data
    7
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 272643 NCBI Gene Model | MGI Sequence Detail 4818 C57BL/6J ±  kb
transcript NM_199471 RefSeq | MGI Sequence Detail 1995 Not Specified  
polypeptide Q76HL1 UniProt | EBI | MGI Sequence Detail 382 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001314 Peptidase S1A, chymotrypsin family
    IPR009003 Peptidase S1, PA clan
    IPR043504 Peptidase S1, PA clan, chymotrypsin-like fold
    IPR001254 Serine proteases, trypsin domain
    IPR018114 Serine proteases, trypsin family, histidine active site
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 1
Other
Accession IDs
less
MGI:2685507
References
more
  • Summaries
    All 17
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
  • Latest
    J:202067 Yoneda R, et al., Three testis-specific paralogous serine proteases play different roles in murine spermatogenesis and are involved in germ cell survival during meiosis. Biol Reprod. 2013 May;88(5):118
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory