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Marchf4 Gene Detail
Summary
  • Symbol
    Marchf4
  • Name
    membrane associated ring-CH-type finger 4
  • Synonyms
    March4, mKIAA1399
  • Feature Type
    protein coding gene
  • IDs
    MGI:2683550
    NCBI Gene: 381270
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:72466271-72576089 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 36.54 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2961 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2683550
 protein coding gene Chr1:72466271-72576454 (-)
129S1/SvImJ ENSMUSG00200003933
 protein coding gene Chr1:70124750-70234572 (-)
A/J ENSMUSG00195031084
 protein coding gene Chr1:69542391-69652160 (-)
AKR/J ENSMUSG00220035907
 protein coding gene Chr1:69694684-69804442 (-)
BALB/cJ ENSMUSG00180028251
 protein coding gene Chr1:69807063-69916907 (-)
C3H/HeJ ENSMUSG00175000722
 protein coding gene Chr1:69937728-70047481 (-)
C57BL/6NJ ENSMUSG00215013090
 protein coding gene Chr1:69852880-69962722 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014244
 protein coding gene Chr1:66042257-66151313 (-)
CAST/EiJ ENSTCUG00005019768
 protein coding gene Chr1:69604677-69714872 (-)
CBA/J ENSMUSG00210003039
 protein coding gene Chr1:69635079-69744912 (-)
DBA/2J ENSMUSG00185004920
 protein coding gene Chr1:70725614-70835364 (-)
FVB/NJ ENSMUSG00205011340
 protein coding gene Chr1:69361687-69471525 (-)
JF1/MsJ ENSUMUG00000003014
 protein coding gene Chr1:69641057-69751507 (-)
LP/J ENSMUSG00230001558
 protein coding gene Chr1:70719850-70829682 (-)
NOD/ShiLtJ ENSMUSG00190013279
 protein coding gene Chr1:69851881-69961744 (-)
NZO/HlLtJ ENSMUSG00225038639
 protein coding gene Chr1:73934946-74044773 (-)
PWK/PhJ ENSLUMG00010007247
 protein coding gene Chr1:69232491-69342362 (-)
SPRET/EiJ ENSMSPG00010017116
 protein coding gene Chr1:71315350-71423227 (-)
WSB/EiJ ENSIUOG00005027237
 protein coding gene Chr1:69503043-69612362 (-)



Homology
more
  • Human Ortholog
    MARCHF4, membrane associated ring-CH-type finger 4
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MARCHF4, membrane associated ring-CH-type finger 4
  • Synonyms
    MARCH4, MARCH-IV, RNF174
  • Links
    NCBI Gene ID: 57574
    UniProt: Q9P2E8

  • Chr Location
    2q35; chr2:216257865-216372483 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    18
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039372 Ensembl Gene Model | MGI Sequence Detail 109819 C57BL/6J ±  kb
transcript ENSMUST00000047786 Ensembl | MGI Sequence Detail 4553 Not Applicable  
polypeptide ENSMUSP00000042803 Ensembl | MGI Sequence Detail 409 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 18

    Microarray probesets 2
Other
Accession IDs
less
MGI:6368852
References
more
  • Summaries
    All 39
    Developmental Gene Expression 1
    Gene Ontology 9
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:228600 Li Q, et al., Stage-dependent and locus-specific role of histone demethylase Jumonji D3 (JMJD3) in the embryonic stages of lung development. PLoS Genet. 2014 Jul;10(7):e1004524
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory