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Klhl23 Gene Detail
Summary
  • Symbol
    Klhl23
  • Name
    kelch-like 23
  • Synonyms
    C130068N17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2683536
    NCBI Gene: 277396
  • Alliance
    genome feature page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:69652288-69666995 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 40.95 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    400 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2683536
 protein coding gene Chr2:69652285-69666995 (+)
129S1/SvImJ ENSMUSG00200036858
 protein coding gene Chr2:66691835-66727228 (+)
A/J ENSMUSG00195020796
 protein coding gene Chr2:66843557-66878446 (+)
AKR/J ENSMUSG00220035497
 protein coding gene Chr2:66808432-66843311 (+)
BALB/cJ ENSMUSG00180037002
 protein coding gene Chr2:66788716-66823362 (+)
C3H/HeJ ENSMUSG00175034508
 protein coding gene Chr2:66908033-66942682 (+)
C57BL/6NJ ENSMUSG00215023545
 protein coding gene Chr2:66728236-66763630 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023628
 protein coding gene Chr2:64349607-64363977 (+)
CAST/EiJ ENSTCUG00005008568
 protein coding gene Chr2:66211502-66242414 (+)
CBA/J ENSMUSG00210033649
 protein coding gene Chr2:66948318-66982969 (+)
DBA/2J ENSMUSG00185036865
 protein coding gene Chr2:66783866-66818515 (+)
FVB/NJ ENSMUSG00205031781
 protein coding gene Chr2:66257349-66292230 (+)
JF1/MsJ ENSUMUG00000003646
 protein coding gene Chr2:66451159-66483428 (+)
LP/J ENSMUSG00230018871
 protein coding gene Chr2:68589338-68623992 (+)
NOD/ShiLtJ ENSMUSG00190031062
 protein coding gene Chr2:66876960-66911831 (+)
NZO/HlLtJ ENSMUSG00225014363
 protein coding gene Chr2:76331597-76366246 (+)
PWK/PhJ ENSLUMG00010030752
 protein coding gene Chr2:66675452-66709306 (+)
SPRET/EiJ ENSMSPG00010032242
 protein coding gene Chr2:68096405-68112385 (+)
WSB/EiJ ENSIUOG00005017836
 protein coding gene Chr2:66921874-66956958 (+)



Homology
more
  • Human Ortholog
    KLHL23, kelch like family member 23
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KLHL23, kelch like family member 23
  • Synonyms
    DITHP
  • Links
    NCBI Gene ID: 151230
    UniProt: Q8NBE8

  • Chr Location
    2q31.1; chr2:169694488-169776989 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    598
  • Tissues
    1
  • cDNA Data
    70
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042155 Ensembl Gene Model | MGI Sequence Detail 14708 C57BL/6J ±  kb
transcript ENSMUST00000053087 Ensembl | MGI Sequence Detail 4617 Not Applicable  
polypeptide ENSMUSP00000050219 Ensembl | MGI Sequence Detail 558 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 70
    cDNA 70

    Microarray probesets 5
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory