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Zfp395 Gene Detail
Summary
  • Symbol
    Zfp395
  • Name
    zinc finger protein 395
  • Synonyms
    BC027382, LOC380912, MGC:60757
  • Feature Type
    protein coding gene
  • IDs
    MGI:2682318
    NCBI Gene: 380912
  • Alliance
    genome feature page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:65595838-65636379 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 34.32 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    974 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2682318
 protein coding gene Chr14:65595796-65636379 (+)
129S1/SvImJ ENSMUSG00200029112
 protein coding gene Chr14:54195096-54235644 (+)
A/J ENSMUSG00195014327
 protein coding gene Chr14:54372548-54413080 (+)
AKR/J ENSMUSG00220030721
 protein coding gene Chr14:53713075-53753617 (+)
BALB/cJ ENSMUSG00180032449
 protein coding gene Chr14:53988740-54029275 (+)
C3H/HeJ ENSMUSG00175030270
 protein coding gene Chr14:55731479-55772038 (+)
C57BL/6NJ ENSMUSG00215020268
 protein coding gene Chr14:53928679-53969229 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019423
 protein coding gene Chr14:56503910-56544528 (+)
CAST/EiJ ENSTCUG00005037075
 protein coding gene Chr14:55626688-55666371 (+)
CBA/J ENSMUSG00210034450
 protein coding gene Chr14:54359904-54400444 (+)
DBA/2J ENSMUSG00185029043
 protein coding gene Chr14:59529296-59569855 (+)
FVB/NJ ENSMUSG00205021840
 protein coding gene Chr14:53875382-53915915 (+)
JF1/MsJ ENSUMUG00000020974
 protein coding gene Chr14:70695779-70736559 (+)
LP/J ENSMUSG00230036393
 protein coding gene Chr14:71558639-71599192 (+)
NOD/ShiLtJ ENSMUSG00190025931
 protein coding gene Chr14:54154636-54195173 (+)
NZO/HlLtJ ENSMUSG00225038489
 protein coding gene Chr14:61887567-61928107 (+)
PWK/PhJ ENSLUMG00010030733
 protein coding gene Chr14:53582883-53623627 (+)
SPRET/EiJ ENSMSPG00010027549
 protein coding gene Chr14:57072780-57114040 (+)
WSB/EiJ ENSIUOG00005034993
 protein coding gene Chr14:53590173-53630685 (+)



Homology
more
  • Human Ortholog
    ZNF395, zinc finger protein 395
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF395, zinc finger protein 395
  • Synonyms
    HDBP-2, HDBP2, HDRF-2, PBF, PRF-1, PRF1, Si-1-8-14
  • Links
    NCBI Gene ID: 55893
    UniProt: Q9H8N7

  • Chr Location
    8p21.1; chr8:28345590-28402701 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    624
  • Tissues
    20
  • cDNA Data
    77
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000034522 Ensembl Gene Model | MGI Sequence Detail 40542 C57BL/6J ±  kb
    transcript ENSMUST00000066994 Ensembl | MGI Sequence Detail 4229 Not Applicable  
    polypeptide ENSMUSP00000064422 Ensembl | MGI Sequence Detail 508 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • InterPro Domains
      IPR013087 Zinc finger C2H2-type
      IPR052253 Zinc finger protein 395/704 and SLC2A4 regulator
      IPR031940 ZNF395/ZNF704, N-terminal domain
    • GlyGen
      E9Q5N9 1 site
    Molecular
    Reagents
    less
    • All nucleic 77
      cDNA 77

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2685756, MGI:3039574
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 2
      Gene Ontology 6
      Phenotypes 12
    • Earliest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory