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Cimap2 Gene Detail
Summary
  • Symbol
    Cimap2
  • Name
    ciliary microtubule associated protein 2
  • Synonyms
    BC055111, Lexm, MGC:58608
  • Feature Type
    protein coding gene
  • IDs
    MGI:2681853
    NCBI Gene: 242602
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:106448106-106474438 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 49.67 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    834 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2681853
 protein coding gene Chr4:106448105-106474594 (-)
129S1/SvImJ ENSMUSG00200026593
 protein coding gene Chr4:101507473-101533831 (-)
A/J ENSMUSG00195042111
 protein coding gene Chr4:102051604-102077561 (-)
AKR/J ENSMUSG00220005902
 protein coding gene Chr4:101458291-101484202 (-)
BALB/cJ ENSMUSG00180032828
 protein coding gene Chr4:100895194-100921051 (-)
C3H/HeJ ENSMUSG00175013273
 protein coding gene Chr4:101899757-101925610 (-)
C57BL/6NJ ENSMUSG00215024139
 protein coding gene Chr4:101780450-101806388 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026234
 protein coding gene Chr4:98672144-98697322 (-)
CAST/EiJ ENSTCUG00005007219
 protein coding gene Chr4:100998555-101024912 (-)
CBA/J ENSMUSG00210027417
 protein coding gene Chr4:101532754-101558605 (-)
DBA/2J ENSMUSG00185043607
 protein coding gene Chr4:102226254-102252151 (-)
FVB/NJ ENSMUSG00205011073
 protein coding gene Chr4:100462306-100488258 (-)
JF1/MsJ ENSUMUG00000034425
 protein coding gene Chr4:102246024-102272332 (-)
LP/J ENSMUSG00230005814
 protein coding gene Chr4:105544342-105570290 (-)
NOD/ShiLtJ ENSMUSG00190030808
 protein coding gene Chr4:100902581-100928437 (-)
NZO/HlLtJ ENSMUSG00225032422
 protein coding gene Chr4:110644836-110671122 (-)
PWK/PhJ ENSLUMG00010018231
 protein coding gene Chr4:99962555-99988688 (-)
SPRET/EiJ ENSMSPG00010023789
 protein coding gene Chr4:102207115-102231591 (-)
WSB/EiJ ENSIUOG00005003018
 protein coding gene Chr4:101109515-101135819 (-)



Homology
more
  • Human Ortholog
    CIMAP2, ciliary microtubule associated protein 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CIMAP2, ciliary microtubule associated protein 2
  • Synonyms
    C1orf177, LEM, LEXM
  • Links
    NCBI Gene ID: 163747
    UniProt: Q3ZCV2

  • Chr Location
    1p32.3; chr1:54806063-54842252 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 2 alleles in 2 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit embryonic lethality. Heterozygous null mice show decreased CD8-positive, alpha-beta T cell number and decreased cytotoxic T cell cytolysis in response to lymphocytic choriomeningitis virus.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000054362 Ensembl Gene Model | MGI Sequence Detail 26333 C57BL/6J ±  kb
    transcript ENSMUST00000189032 Ensembl | MGI Sequence Detail 1549 Not Applicable  
    polypeptide ENSMUSP00000139868 Ensembl | MGI Sequence Detail 414 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 3
      cDNA 3

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:7482233
    References
    more
    • Summaries
      All 26
      Phenotypes 11
    • Earliest
      J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
    • Latest
      J:223336 Okoye I, et al., T cell metabolism. The protein LEM promotes CD8(+) T cell immunity through effects on mitochondrial respiration. (Expression of Concern 350 (6267): 1482). Science. 2015 May 29;348(6238):995-1001
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory