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Urb2 Gene Detail
Summary
  • Symbol
    Urb2
  • Name
    URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
  • Synonyms
    mKIAA0133
  • Feature Type
    protein coding gene
  • IDs
    MGI:2681124
    NCBI Gene: 382038
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:124748247-124775244 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 72.33 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    676 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2681124
 protein coding gene Chr8:124748236-124775244 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034268
 protein coding gene Chr8:127672461-127701312 (+)
A/J MGP_AJ_G0034248
 protein coding gene Chr8:122407858-122435585 (+)
AKR/J MGP_AKRJ_G0034175
 protein coding gene Chr8:125926220-125954669 (+)
BALB/cJ MGP_BALBcJ_G0034241
 protein coding gene Chr8:122593545-122621495 (+)
C3H/HeJ MGP_C3HHeJ_G0033952
 protein coding gene Chr8:126560453-126588404 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034761
 protein coding gene Chr8:131965579-131993095 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031702
 protein coding gene Chr8:115183806-115210615 (+)
CAST/EiJ MGP_CASTEiJ_G0033279
 protein coding gene Chr8:126677490-126707281 (+)
CBA/J MGP_CBAJ_G0033925
 protein coding gene Chr8:136785339-136818522 (+)
DBA/2J MGP_DBA2J_G0034081
 protein coding gene Chr8:121558742-121586028 (+)
FVB/NJ MGP_FVBNJ_G0034025
 protein coding gene Chr8:120728070-120755240 (+)
LP/J MGP_LPJ_G0034170
 protein coding gene Chr8:127833521-127865429 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034072
 protein coding gene Chr8:138907992-138935536 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034780
 protein coding gene Chr8:126163894-126193689 (+)
PWK/PhJ MGP_PWKPhJ_G0032981
 protein coding gene Chr8:121318617-121346860 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032820
 protein coding gene Chr8:124802196-124828710 (+)
WSB/EiJ MGP_WSBEiJ_G0033396
 protein coding gene Chr8:126887988-126914476 (+)



Homology
more
  • Human Ortholog
    URB2, URB2 ribosome biogenesis homolog
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    URB2, URB2 ribosome biogenesis homolog
  • Synonyms
    KIAA0133, NET10, NPA2
  • Links
    NCBI Gene ID: 9816
    UniProt: Q14146

  • Chr Location
    1q42.13; chr1:229626247-229660200 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    2
  • cDNA Data
    67
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031976 Ensembl Gene Model | MGI Sequence Detail 26998 C57BL/6J ±  kb
transcript ENSMUST00000034457 Ensembl | MGI Sequence Detail 5853 Not Applicable  
polypeptide ENSMUSP00000034457 Ensembl | MGI Sequence Detail 1524 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR018849 Nucleolar 27S pre-rRNA processing, Urb2/Npa2, C-terminal
    IPR052609 Ribosome Biogenesis Regulator
Molecular
Reagents
less
  • All nucleic 67
    cDNA 67

    Microarray probesets 4
Other
Accession IDs
less
MGI:2142845
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/09/2025
MGI 6.24 		The Jackson Laboratory