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Tmem150b Gene Detail
Summary
  • Symbol
    Tmem150b
  • Name
    transmembrane protein 150B
  • Synonyms
    MGC:31268, Tmem224
  • Feature Type
    protein coding gene
  • IDs
    MGI:2679718
    NCBI Gene: 330460
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:4709831-4728248 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 2.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    104 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2679718
 protein coding gene Chr7:4709831-4728250 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031556
 protein coding gene Chr7:1632655-1652884 (-)
A/J MGP_AJ_G0031530
 protein coding gene Chr7:1638879-1658955 (-)
AKR/J MGP_AKRJ_G0031459
 protein coding gene Chr7:1706771-1728886 (-)
BALB/cJ MGP_BALBcJ_G0031538
 protein coding gene Chr7:1682526-1701114 (-)
C3H/HeJ MGP_C3HHeJ_G0031259
 protein coding gene Chr7:1680506-1700937 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031999
 protein coding gene Chr7:1692820-1715423 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029123
 protein coding gene Chr7:1389168-1406739 (-)
CAST/EiJ MGP_CASTEiJ_G0030623
 protein coding gene Chr7:1621837-1641265 (-)
CBA/J MGP_CBAJ_G0031217
 protein coding gene Chr7:1887088-1915459 (-)
DBA/2J MGP_DBA2J_G0031376
 protein coding gene Chr7:1621201-1639978 (-)
FVB/NJ MGP_FVBNJ_G0031328
 protein coding gene Chr7:1586520-1605643 (-)
LP/J MGP_LPJ_G0031461
 protein coding gene Chr7:1742579-1761886 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031367
 protein coding gene Chr7:1831432-1851435 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032029
 protein coding gene Chr7:1620803-1640583 (-)
PWK/PhJ MGP_PWKPhJ_G0030351
 protein coding gene Chr7:1789298-1808411 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030176
 protein coding gene Chr7:1667595-1690206 (-)
WSB/EiJ MGP_WSBEiJ_G0030718
 protein coding gene Chr7:1636408-1655588 (-)



Homology
more
  • Human Ortholog
    TMEM150B, transmembrane protein 150B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM150B, transmembrane protein 150B
  • Synonyms
    DRAM3, TMEM224, TTN2
  • Links
    NCBI Gene ID: 284417
    neXtProt AC: NX_A6NC51
    UniProt: A6NC51

  • Chr Location
    19q13.42; chr19:55309444-55334048 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 2 alleles in 2 genetic backgrounds
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice exhibit normal female fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
DNA-templated transcription
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000046456 Ensembl Gene Model | MGI Sequence Detail 18418 C57BL/6J ±  kb
    transcript ENSMUST00000086363 Ensembl | MGI Sequence Detail 1341 Not Applicable  
    polypeptide ENSMUSP00000083549 Ensembl | MGI Sequence Detail 238 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 6

      Microarray probesets 4
    References
    more
    • Summaries
      All 28
      Gene Ontology 2
      Phenotypes 7
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:299547 Liu R, et al., TMEM150B is dispensable for oocyte maturation and female fertility in mouse. Sci Rep. 2020 Dec 7;10(1):21381
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/28/2023
    MGI 6.22     		The Jackson Laboratory