Dbpht2 Gene Detail

Summary

• Symbol
  Dbpht2
• Name
  DNA binding protein with his-thr domain
• Synonyms
  Spot2

• Feature Type
  protein coding gene
  BioType Conflict
  
• IDs
  MGI:2679513
  NCBI Gene: 386753
• Alliance
  genome feature page
• Transcription Start Sites
  4 TSS

Location &
Maps

• Sequence Map
  Chr12:74344248-74347242 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 12, 32.46 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  112 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2679513	protein coding gene	Chr12:74343442-74348782 (+)
129S1/SvImJ	ENSMUSG00200032223	lncRNA gene	Chr12:66271946-66277301 (+)
A/J	ENSMUSG00195015246	lncRNA gene	Chr12:68974856-68980213 (+)
AKR/J	ENSMUSG00220015415	lncRNA gene	Chr12:66765747-66771089 (+)
BALB/cJ	ENSMUSG00180036224	lncRNA gene	Chr12:67960947-67966290 (+)
C3H/HeJ	ENSMUSG00175029500	lncRNA gene	Chr12:71100517-71105871 (+)
C57BL/6NJ	ENSMUSG00215034606	lncRNA gene	Chr12:67336742-67342083 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017851	protein coding gene	Chr12:68893903-68896875 (+)
CAST/EiJ	ENSTCUG00005038134	lncRNA gene	Chr12:67285456-67290805 (+)
CBA/J	ENSMUSG00210030653	lncRNA gene	Chr12:67527956-67533313 (+)
DBA/2J	ENSMUSG00185004979	lncRNA gene	Chr12:69426180-69431520 (+)
FVB/NJ	ENSMUSG00205037471	lncRNA gene	Chr12:67158582-67163909 (+)
JF1/MsJ	ENSUMUG00000023298	lncRNA gene	Chr12:73399684-73405081 (+)
LP/J	ENSMUSG00230022355	lncRNA gene	Chr12:76399448-76404803 (+)
NOD/ShiLtJ	ENSMUSG00190013088	lncRNA gene	Chr12:66591788-66597129 (+)
NZO/HlLtJ	ENSMUSG00225038971	lncRNA gene	Chr12:78453848-78459203 (+)
PWK/PhJ	ENSLUMG00010033131	lncRNA gene	Chr12:67460889-67466257 (+)
SPRET/EiJ	ENSMSPG00010030620	lncRNA gene	Chr12:69177908-69183236 (+)
WSB/EiJ	ENSIUOG00005013252	lncRNA gene	Chr12:67223660-67229008 (+)

Homology

• Gene Tree
  Dbpht2
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  2
• Chemically induced (other)
  1
• Endonuclease-mediated
  1
• Genomic Mutations
  1 involving Dbpht2
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  7 strains or lines available

Expression

• Assay Results
  623
• Tissues
  21
• cDNA Data
  5
• Literature Summary
  2

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  33
• RefSeq
  2
• UniProt
  3
• CCDS
  CCDS25979.1

• Ensembl
  ENSMUSG00000029878 (Evidence)
• NCBI Gene
  386753

Representative Sequences			Length	Strain/Species
genomic	386753	NCBI Gene Model | MGI Sequence Detail	2995	C57BL/6J
transcript	NM_198866	RefSeq | MGI Sequence Detail	2995	Not Specified
polypeptide	NP_942566	RefSeq | MGI Sequence Detail	128	Not Specified

Protein
Information

• UniProt
  3 Sequences

Molecular
Reagents

• All nucleic 7

  Genomic 2

  cDNA 5

  
  

  Microarray probesets 1

References

• Summaries
  All 19

  Developmental Gene Expression 2

  Phenotypes 5
• Earliest
  J:84010 Miyamoto T, et al., Molecular cloning and expression analysis of the mouse Spot-2 gene in pituitary development. Dev Genes Evol. 2003 May;213(4):199-202
• Latest
  J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Dbpht2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr113885	Chr12:74343466-74343471 (+)	-779 bp
Tssr113886	Chr12:74343632-74343635 (+)	-614 bp
Tssr113887	Chr12:74345097-74345108 (+)	855 bp
Tssr113888	Chr12:74345552-74345563 (+)	1,310 bp