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Focad Gene Detail
Summary
  • Symbol
    Focad
  • Name
    focadhesin
  • Synonyms
    BC057079, mKIAA1797
  • Feature Type
    protein coding gene
  • IDs
    MGI:2676921
    NCBI Gene: 230393
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:88012866-88329248 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 41.40 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1519 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676921
 protein coding gene Chr4:88012858-88329248 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028419
 protein coding gene Chr4:87934075-88276760 (+)
A/J MGP_AJ_G0028380
 protein coding gene Chr4:84895039-85202126 (+)
AKR/J MGP_AKRJ_G0028329
 protein coding gene Chr4:86986388-87315781 (+)
BALB/cJ MGP_BALBcJ_G0028400
 protein coding gene Chr4:85096414-85410269 (+)
C3H/HeJ MGP_C3HHeJ_G0028115
 protein coding gene Chr4:87711830-88028312 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028839
 protein coding gene Chr4:91322583-91653218 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026139
 protein coding gene Chr4:80901199-81195187 (+)
CAST/EiJ MGP_CASTEiJ_G0027556
 protein coding gene Chr4:85562158-85875171 (+)
CBA/J MGP_CBAJ_G0028084
 protein coding gene Chr4:94138463-94481730 (+)
DBA/2J MGP_DBA2J_G0028233
 protein coding gene Chr4:84652088-84958222 (+)
FVB/NJ MGP_FVBNJ_G0028199
 protein coding gene Chr4:83598680-83920815 (+)
LP/J MGP_LPJ_G0028333
 protein coding gene Chr4:88300256-88640231 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028228
 protein coding gene Chr4:99124552-99472318 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028876
 protein coding gene Chr4:87113276-87443692 (+)
PWK/PhJ MGP_PWKPhJ_G0027279
 protein coding gene Chr4:82988299-83286205 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027104
 protein coding gene Chr4:84617289-84952450 (+)
WSB/EiJ MGP_WSBEiJ_G0027632
 protein coding gene Chr4:87335561-87648823 (+)



Homology
more
  • Human Ortholog
    FOCAD, focadhesin
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FOCAD, focadhesin
  • Synonyms
    KIAA1797, SCOLIV
  • Links
    NCBI Gene ID: 54914
    neXtProt AC: NX_Q5VW36
    UniProt: Q5VW36

  • Chr Location
    9p21.3; chr9:20655625-20995955 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    713
  • Tissues
    4
  • cDNA Data
    59
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000038368 Ensembl Gene Model | MGI Sequence Detail 316383 C57BL/6J ±  kb
    transcript ENSMUST00000097992 Ensembl | MGI Sequence Detail 5791 Not Applicable  
    polypeptide ENSMUSP00000095602 Ensembl | MGI Sequence Detail 1798 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 60
      cDNA 60

      Microarray probesets 3
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 3
      Gene Ontology 4
      Phenotypes 11
    • Earliest
      J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
    • Latest
      J:310838 Liu D, et al., PRICKLE1 x FOCAD Interaction Revealed by Genome-Wide vQTL Analysis of Human Facial Traits. Front Genet. 2021;12:674642
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory