Mir128-1 MGI Mouse Gene Detail - MGI:2676813

Symbol

Mir128-1
Name

microRNA 128-1
Synonyms

Mirn128, Mirn128-1, Mirn128a, mmu-mir-128-1, mmu-mir-128a

Feature Type

miRNA gene
IDs

MGI:2676813
NCBI Gene: 387147
Alliance

genome feature page
Transcription Start Sites

1 TSS

Sequence Map

Chr1:128130098-128130167 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 55.80 cM
Mapping Data

1 experiment

SNPs within 2kb

64 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2676813	miRNA gene	Chr1:128130098-128130167 (+)
129S1/SvImJ	ENSMUSG00200009733	miRNA gene	Chr1:125684350-125684419 (+)
A/J	ENSMUSG00195044274	miRNA gene	Chr1:124768834-124768903 (+)
AKR/J	ENSMUSG00220050524	miRNA gene	Chr1:124620768-124620837 (+)
BALB/cJ	ENSMUSG00180038959	miRNA gene	Chr1:125338550-125338619 (+)
C3H/HeJ	ENSMUSG00175046069	miRNA gene	Chr1:125037479-125037548 (+)
C57BL/6NJ	ENSMUSG00215046321	miRNA gene	Chr1:125051586-125051655 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0006968	miRNA gene	Chr1:119893955-119894024 (+)
CAST/EiJ	ENSTCUG00005040044	miRNA gene	Chr1:123968455-123968524 (+)
CBA/J	ENSMUSG00210028046	miRNA gene	Chr1:124917888-124917957 (+)
DBA/2J	ENSMUSG00185002037	miRNA gene	Chr1:129282713-129282782 (+)
FVB/NJ	ENSMUSG00205046806	miRNA gene	Chr1:124242994-124243063 (+)
JF1/MsJ	ENSUMUG00000003056	miRNA gene	Chr1:128412372-128412441 (+)
LP/J	ENSMUSG00230001195	miRNA gene	Chr1:128862697-128862766 (+)
NOD/ShiLtJ	ENSMUSG00190047263	miRNA gene	Chr1:124921030-124921099 (+)
NZO/HlLtJ	ENSMUSG00225004769	miRNA gene	Chr1:132598278-132598347 (+)
PWK/PhJ	ENSLUMG00010029940	miRNA gene	Chr1:124045252-124045321 (+)
SPRET/EiJ	ENSMSPG00010045429	miRNA gene	Chr1:126817952-126818021 (+)
WSB/EiJ	ENSIUOG00005049050	miRNA gene	Chr1:124636890-124636959 (+)

Human Ortholog

MIR128-1, microRNA 128-1

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR128-1, microRNA 128-1
Synonyms

mir-128-1, MIR128A, MIRN128-1, MIRN128A
Links

HGNC:31510

NCBI Gene ID: 406915
Chr Location

chr2:135665397-135665478 (+) GRCh38

MGI Vertebrate Homology

Mir128-1 stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: MIR128-1
Gene Tree

Mir128-1

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
9 phenotype references

All Mutations and Alleles

7
Chemically induced (other)

2
Endonuclease-mediated

1
Radiation induced

1
Targeted

3
Genomic Mutations

3 involving Mir128-1
Find Mice (IMSR)

1 strains or lines available

Mice homozygous for a knock-out allele are viable and behaviorally normal.

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All GO Annotations

4
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

653
Tissues

32
Literature Summary

15

Images

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

25
RefSeq

1

Ensembl

ENSMUSG00000065520 (Evidence)
NCBI Gene

387147

Representative Sequences				Length	Strain/Species	Flank
	genomic	387147	NCBI Gene Model \| MGI Sequence Detail	70	C57BL/6J	± kb
	transcript	NR_029543	RefSeq \| MGI Sequence Detail	70	C57BL/6

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All nucleic 8

Primer pair 3

Other 5

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miRBase

MI0000155

Summaries

All 45

Developmental Gene Expression 15

Gene Ontology 4

Phenotypes 9
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:377036 Ko JY, et al., Cartilage-specific knockout of miRNA-128a expression normalizes the expression of circadian clock genes (CCGs) and mitigates the severity of osteoarthritis. Biomed J. 2024 Apr;47(2):100629

TSS for Mir128-1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr8522	Chr1:128130159-128130166 (+)	65 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/08/2026 MGI 6.24