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Dnajc13 Gene Detail
Summary
  • Symbol
    Dnajc13
  • Name
    DnaJ heat shock protein family (Hsp40) member C13
  • Synonyms
    D030002L11Rik, LOC382100, mKIAA0678, Rme8
  • Feature Type
    protein coding gene
  • IDs
    MGI:2676368
    NCBI Gene: 235567
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:104028481-104140129 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 56.61 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    852 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676368
 protein coding gene Chr9:104028481-104140807 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035207
 protein coding gene Chr9:105807244-105918977 (-)
A/J MGP_AJ_G0035187
 protein coding gene Chr9:102004112-102114216 (-)
AKR/J MGP_AKRJ_G0035119
 protein coding gene Chr9:104536841-104645773 (-)
BALB/cJ MGP_BALBcJ_G0035180
 protein coding gene Chr9:101717960-101823253 (-)
C3H/HeJ MGP_C3HHeJ_G0034890
 protein coding gene Chr9:104917579-105024470 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035700
 protein coding gene Chr9:108735462-108845163 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032598
 protein coding gene Chr9:99571251-99677934 (-)
CAST/EiJ MGP_CASTEiJ_G0034202
 protein coding gene Chr9:104799339-104906523 (-)
CBA/J MGP_CBAJ_G0034859
 protein coding gene Chr9:112523761-112642310 (-)
DBA/2J MGP_DBA2J_G0035020
 protein coding gene Chr9:101486810-101596231 (-)
FVB/NJ MGP_FVBNJ_G0034968
 protein coding gene Chr9:100292787-100398311 (-)
LP/J MGP_LPJ_G0035096
 protein coding gene Chr9:106015139-106124460 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035007
 protein coding gene Chr9:114288965-114397573 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035722
 protein coding gene Chr9:104774095-104880836 (-)
PWK/PhJ MGP_PWKPhJ_G0033909
 protein coding gene Chr9:101773769-101881019 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033744
 protein coding gene Chr9:104851477-104965700 (-)
WSB/EiJ MGP_WSBEiJ_G0034322
 protein coding gene Chr9:104660430-104769429 (-)



Homology
more
  • Human Ortholog
    DNAJC13, DnaJ heat shock protein family (Hsp40) member C13
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DNAJC13, DnaJ heat shock protein family (Hsp40) member C13
  • Synonyms
    PARK21, RME8
  • Links
    NCBI Gene ID: 23317
    neXtProt AC: NX_O75165
    UniProt: O75165

  • Chr Location
    3q22.1; chr3:132417527-132539032 (+)  GRCh38.p7
Human Diseases
more
  • Diseases
    2 with human DNAJC13 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    1
  • cDNA Data
    149
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000032560 Ensembl Gene Model | MGI Sequence Detail 111649 C57BL/6J ±  kb
    transcript ENSMUST00000186788 Ensembl | MGI Sequence Detail 6747 Not Applicable  
    polypeptide ENSMUSP00000139804 Ensembl | MGI Sequence Detail 2248 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 149
      cDNA 149

      Microarray probesets 9
    Other
    Accession IDs
    less
    MGI:2685970
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 10
    • Earliest
      J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
    • Latest
      J:282550 Follett J, et al., DNAJC13 p.Asn855Ser, implicated in familial parkinsonism, alters membrane dynamics of sorting nexin 1. Neurosci Lett. 2019 Jul 27;706:114-122
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    05/30/2023
    MGI 6.22     		The Jackson Laboratory