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Dio3os Gene Detail
Summary
  • Symbol
    Dio3os
  • Name
    deiodinase, iodothyronine type III, opposite strand
  • Synonyms
    Dio3as, Dio3os
Location &
Maps
more
  • Sequence Map
    Chr12:110241818-110244502 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 60.56 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    132 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2664395
 bidirectional promoter lncRNA gene Chr12:110241813-110244609 (-)
129S1/SvImJ ENSMUSG00200026730
 lncRNA gene Chr12:102016311-102019102 (-)
A/J ENSMUSG00195045256
 lncRNA gene Chr12:104535257-104538062 (-)
AKR/J ENSMUSG00220042412
 lncRNA gene Chr12:102430957-102433741 (-)
BALB/cJ ENSMUSG00180049257
 lncRNA gene Chr12:103779380-103782171 (-)
C3H/HeJ ENSMUSG00175049776
 lncRNA gene Chr12:106347593-106350384 (-)
C57BL/6NJ ENSMUSG00215050618
 lncRNA gene Chr12:103052263-103055054 (-)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005019984
 lncRNA gene Chr12:102528086-102530877 (-)
CBA/J ENSMUSG00210034261
 lncRNA gene Chr12:103409033-103411824 (-)
DBA/2J ENSMUSG00185030723
 lncRNA gene Chr12:105243403-105246188 (-)
FVB/NJ ENSMUSG00205043859
 lncRNA gene Chr12:102464199-102466990 (-)
JF1/MsJ ENSUMUG00000027438
 lncRNA gene Chr12:109995592-109998375 (-)
LP/J ENSMUSG00230030917
 lncRNA gene Chr12:112281000-112283791 (-)
NOD/ShiLtJ ENSMUSG00190032013
 lncRNA gene Chr12:82764602-82767387 (+)
NZO/HlLtJ ENSMUSG00225038468
 lncRNA gene Chr12:114029160-114031951 (-)
PWK/PhJ ENSLUMG00010050476
 lncRNA gene Chr12:103458700-103461485 (-)
SPRET/EiJ ENSMSPG00010023513
 lncRNA gene Chr12:105750328-105753120 (-)
WSB/EiJ ENSIUOG00005010356
 lncRNA gene Chr12:102451055-102453848 (-)



Homology
more
  • Human Ortholog
    DIO3OS, DIO3 opposite strand upstream RNA
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DIO3OS, DIO3 opposite strand upstream RNA
  • Synonyms
    C14orf134, DIO3-AS1, DIO3-OS, NCRNA00041
  • Links
    NCBI Gene ID: 64150

  • Chr Location
    14q32.31; chr14:101552221-101620355 (-)  GRCh38
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    632
  • Tissues
    28
  • cDNA Data
    6
  • Literature Summary
    5
Sequences &
Gene Models
less
  • All Sequences
    41
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 353504 NCBI Gene Model | MGI Sequence Detail 2685 C57BL/6J ±  kb
transcript NR_002866 RefSeq | MGI Sequence Detail 1280 Not Specified  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 9
    cDNA 7
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145045
References
more
  • Summaries
    All 20
    Developmental Gene Expression 5
    Gene Ontology 1
  • Earliest
    J:80434 Hernandez A, et al., The gene locus encoding iodothyronine deiodinase type 3 (Dio3) is imprinted in the fetus and expresses antisense transcripts. Endocrinology. 2002 Nov;143(11):4483-6
  • Latest
    J:345198 Chen YT, et al., Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance. Nat Commun. 2021 Nov 25;12(1):6845
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory