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Mrpl21 Gene Detail
Summary
  • Symbol
    Mrpl21
  • Name
    mitochondrial ribosomal protein L21
  • Synonyms
    MGC:41352
  • Feature Type
    protein coding gene
  • IDs
    MGI:2660674
    NCBI Gene: 353242
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:3332997-3342837 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 19, 3.05 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    228 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2660674
protein coding gene Chr19:3332901-3342837 (+)
129S1/SvImJ ENSMUSG00200049966
protein coding gene Chr19:91406-101342 (+)
A/J ENSMUSG00195050680
protein coding gene Chr19:482254-492190 (+)
AKR/J ENSMUSG00220036971
protein coding gene Chr19:255273-265208 (+)
BALB/cJ ENSMUSG00180035943
protein coding gene Chr19:857033-866978 (+)
C3H/HeJ ENSMUSG00175008632
protein coding gene Chr19:101831-111766 (+)
C57BL/6NJ ENSMUSG00215039654
protein coding gene Chr19:329634-339572 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022464
protein coding gene Chr19:31545-41492 (+)
CAST/EiJ ENSTCUG00005038757
protein coding gene Chr19:239759-249715 (+)
CBA/J ENSMUSG00210041734
protein coding gene Chr19:101718-111654 (+)
DBA/2J ENSMUSG00185043811
protein coding gene Chr19:478037-487973 (+)
FVB/NJ ENSMUSG00205026876
protein coding gene Chr19:472183-482131 (+)
JF1/MsJ ENSUMUG00000037108
protein coding gene Chr19:464292-474151 (+)
LP/J ENSMUSG00230054082
protein coding gene Chr19:1397628-1407564 (+)
NOD/ShiLtJ ENSMUSG00190028062
protein coding gene Chr19:23334-33381 (+)
NZO/HlLtJ ENSMUSG00225024954
protein coding gene Chr19:5106488-5116424 (+)
PWK/PhJ ENSLUMG00010003640
protein coding gene Chr19:231192-241091 (+)
SPRET/EiJ ENSMSPG00010049721
protein coding gene Chr19:222829-232773 (+)
WSB/EiJ ENSIUOG00005039657
protein coding gene Chr19:97882-107824 (+)



Homology
more
  • Human Ortholog
    MRPL21, mitochondrial ribosomal protein L21
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPL21, mitochondrial ribosomal protein L21
  • Synonyms
    bL21m, L21mt, MRP-L21
  • Links
    NCBI Gene ID: 219927
    UniProt: Q7Z2W9

  • Chr Location
    11q13.3; chr11:68891276-68903835 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 353242 NCBI Gene Model | MGI Sequence Detail 9841 C57BL/6J ±  kb
transcript NM_172252 RefSeq | MGI Sequence Detail 997 C57BL/6  
polypeptide Q9D1N9 UniProt | EBI | MGI Sequence Detail 209 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 86
    cDNA 83
    Primer pair 2
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 38
    Developmental Gene Expression 3
    Gene Ontology 10
    Phenotypes 6
  • Earliest
    J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
  • Latest
    J:297050 Cheong A, et al., Expression analysis of mammalian mitochondrial ribosomal protein genes. Gene Expr Patterns. 2020 Sep 25;38:119147

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory